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Medicina Interna
Print version ISSN 0872-671X
Abstract
PEDRO, Bruno et al. Follicular Dendritic Cell Sarcoma in Mesentery Lymph Node: A Case Report. Medicina Interna [online]. 2016, vol.23, n.4, pp.45-50. ISSN 0872-671X.
Follicular dendritic cell sarcoma is an extremely rare neoplasm, with only few published cases. Remaining under-recognized, misdiagnosis is common. Considered of intermediate malignant potential, it can involve lymph nodes or extranodal sites. This tumor is a diagnostic challenge that requires confirmation through immunohistochemical methods. The treatment is not well established due to limited clinical experience, but is based on surgical excision. We describe a case of a 50-year-old-woman, previously healthy, with gradual complaints of weight loss, anorexia, asthenia, left abdominal pain and fever. The complementary study was inconclusive, until computed tomographic scan showed a nodular lesion on the left flank at the level of the mesentery. She was submitted to an aspiration biopsy with unsatisfactory results so the patient underwent successful surgical excision of the tumor. Histopathological examination revealed neoplasm composed of spindled cells, with marked pleomorphism and numerous mitotic figures and immunohistochemical study allowed the final diagnosis.
Keywords : Lymph Nodes; Immunohistochemistry; Follicular Dendritic Cells Sarcoma.