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Jornal Português de Gastrenterologia
Print version ISSN 0872-8178
Abstract
OSORIO, M. J. et al. Diabetes Mellitus após Terapêutica com Peginterferão-Alfa 2ª para Hepatite Viral C Crónica. J Port Gastrenterol. [online]. 2007, vol.14, n.3, pp.147-149. ISSN 0872-8178.
It has been reported the existence of an association between Chronic Viral Hepatitis C and type 2 Diabetes mellitus, probably as a manifestation of the chronic hepatic disease and/or one of its extra-hepatic manifestations. Recently, it has been reported the appearance of type 1 Diabetes mellitus after treatment with interferon-alpha, associated with the appearance of anti-pancreatic antibodies or with an increase in their titration. We pretend to illustrate a severe case of new-onset type 1 diabetes mellitus, 5 months after combined treatment with interferon-alpha and ribavirin. Our objective is to enhance the importance of evaluate the risk of developing diabetes mellitus with the treatment.