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Portuguese Journal of Nephrology & Hypertension
Print version ISSN 0872-0169
Abstract
SILVA, Ana Paula; FRAGOSO, André and NEVES, Pedro Leão. Relationship of Vitamin D with Diabetes Mellitus and Diabetic Nephropathy. Port J Nephrol Hypert [online]. 2014, vol.28, n.2, pp.108-118. ISSN 0872-0169.
Diabetic nephropathy (DN) is a major public health problem whose prevalence has been increasing in recent years. It is characterized by a progressive pattern and is associated with high morbidity and mortality rates. Several factors are associated with the onset and progression of DN, such as glycaemic control, hypertension, obesity and inflammation status. In addition, vitamin D also seems to be involved through a pleiotropic regulatory activity/protection with promising applicability, either in prevention or progression of renal disease. The purpose of this review was to summarize the scientific evidence that supports the role of vitamin D in diabetes mellitus and DN
Keywords : Diabetes mellitus; diabetic nephropathy; vitamin D.