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Revista Onconews
Print version ISSN 1646-7868On-line version ISSN 2183-6914
Abstract
LIMA, Ana Victória Mota and LIMA, Wenderson Pinheiro de. TREATMENT OF TRIPLE NEGATIVE BREAST CANCER AND IMPACT ON PATIENT SURVIVAL. Revista Onconews [online]. 2022, n.45, e054. Epub Dec 28, 2022. ISSN 1646-7868. https://doi.org/10.31877/on.2022.45.02.
Describe the therapeutic options available and analyze the life expectancy of women diagnosed with triple-negative breast cancer. This was a systematic literature review, the search platforms LILACS, BVS, PubMed and Periódicos capes were used to find articles published from 2015 to 2021 in Portuguese, English and Spanish languages. The keywords "triple negative breast cancer" and "life expectancy" were applied, using the Boolean operator AND. In the end 14 studies were selected that fit the inclusion criteria. Triple-negative breast cancer has limited therapeutic options due to its immunohistochemical classification, thus being constantly subjected to chemotherapy, radiotherapy and surgical procedures that leave the patient weakened. However, other methodologies such as immunotherapy and the use of drugs with different therapeutic targets are under development. Preliminary results show an increase in patient survival and the possibility of a promising future in the therapy of triple negative tumor.
Keywords : Triple-negative neoplasia; Antineoplastics; Immunohistochemistry.