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GE-Portuguese Journal of Gastroenterology
Print version ISSN 2341-4545
Abstract
SARAIVA, Rita Ornelas et al. Refractory Hidradenitis Suppurativa: A Diagnosis to Consider. GE Port J Gastroenterol [online]. 2024, vol.31, n.1, pp.60-64. Epub Mar 01, 2024. ISSN 2341-4545. https://doi.org/10.1159/000528432.
Hidradenitis suppurativa is a chronic inflammatory disease associated with multiple comorbidities, and its association with lymphoma has recently been a topic of debate. However, it is still controversial whether this risk can be attributed to the disease itself or whether it has any relationship with immunosuppressive treatment. Here, we describe the case of a patient with severe perianal hidradenitis suppurativa treated with methotrexate and infliximab, whose exacerbation with persistence of severe symptoms refractory to adequate treatment led to the diagnosis of diffuse large non-Hodgkin B-cell lymphoma. It was decided to perform a colostomy to improve perianal sepsis, and immunochemotherapy was proposed.
Keywords : Hidradenitis suppurativa; Lymphoma; Lymphoproliferative disorder; Methotrexate; Infliximab.