BENTO, Claudia et al. Very elderly patients on haemodialysis: Evolution and its relation with comorbidities. []. , 28, 4, pp.325-329. ISSN 0872-0169.

^len^aIntroduction: The population ageing has conditioned a progressive increase of very old patients on haemodialysis. These patients present multiple comorbidities that worsen the prognosis in dialysis and have an impact on their quality of life. Material and Methods: A retrospective observational study was performed, analysing all patients over 80 years of age that started regular haemodialysis between January 2004 and December 2011. The comorbidities were stratified using the Charlson score and correlated with mortality. Survival analysis was performed with Kaplan-Meier curves. Results: Fifty-nine patients were included, 35 females and 24 males, with a mean age of 84 ± 3 years. At the start of dialysis, the estimated glomerular filtration rate calculated using the modification of diet in renal disease (MDRD) formula was 10.8 ± 2.5 mL/min /1.73 m2. The initial Charlson score was 8 ± 3 and became higher at the end of follow-up (11.5 ± 2.9; p < 0.01). A Charlson score ≥ 8 was associated with more hospitalization days (878 vs. 360; p < 0.005). The survival rate was 56 % at 12 months and 31% at 24 months. The mortality rate at the end of follow-up (20.4 ± 15.7 months) was 55.9%, with a mortality rate of 27.3% at 3 months. The patients with early death presented a higher Charlson score (13.0 ± 1.7 vs. 6.4 ± 1.2; p < 0.01) at the beginning of dialysis. Conclusion: The benefits of dialysis in survival and quality of life in very elderly patients have been questioned. In our series, more than 1/4 of the patients died in the first 3 months of dialysis, corresponding to higher comorbidity scores. The use of comorbidity scores like the Charlson’s may assist in the assessment of the short-term prognosis, but the individualized decision should prevail in all cases.^lpt^aIntrodução: O envelhecimento populacional tem condicionado um aumento progressivo de doentes muito idosos em hemodialise. Estes doentes apresentam multiplas comorbilidades que agravam o prognostico em  dialise e que tem impacto na sua qualidade de vida. Material e Métodos: Estudo observacional retrospetivo de doentes integrados em programa regular de hemodialise com idade igual ou superior a 80 anos entre janeiro/2004 e dezembro/2011. As comorbilidades foram estratificadas utilizando o score de Charlson e relacionadas com a mortalidade. Na analise de sobrevida foram utilizadas as curvas de Kaplan-Meier. Resultados: Foram avaliados 59 doentes, 35 do sexo feminino e 24 do sexo masculino, com 84 ± 3 anos. A data de inclusao em programa regular de hemodialise a taxa de filtracao glomerular calculada pela formula MDRD era de 10,8 ± 2,5 ml/minuto. O score inicial de Charlson era de 8 ± 3 e aumentou no final do follow-up para 11,5 2,9; p < 0,01. Um score de Charlson igual ou superior a 8 associou-se a maior numero de dias de internamento (878 vs. 360; p < 0,005) e a uma sobrevida de 56% aos 12 meses e 31% aos 24 meses. A mortalidade ate ao final do follow-up (20,4 15,7 meses) foi de 55,9 %, com uma mortalidade precoce (< 3 meses) de 27,3 %. Este ultimo grupo apresentava um score de Charlson mais elevado no inicio de dialise (13,0 ± 1,7 vs. 6,4 1,2; p < 0,01). Conclusão: Os beneficios da dialise na sobrevida e qualidade de vida dos doentes muito idosos tem sido questionados . Na nossa serie, mais de ¼ dos doentes faleceram nos primeiros 3 meses, correspondendo a scores de comorbilidade mais elevados. Indices de comorbilidade como o de Charlson podem auxiliar na determinacao do prognostico vital a curto prazo, mas a decisao individualizada deve sempre prevalecer.

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