GONCALVES, Daniel; FIGUEIREDO, Margarida; CARVALHO, Sónia    CARVALHO, Fernanda. Cholinergic urticaria: case report. []. , 19, 4, pp.289-291. ISSN 0872-0754.

Introduction: Cholinergic urticaria is characterized by highly pruritic small (1-3 mm) wheals, that occur after raising the body temperature. Case Report: The authors report the case of a 14-year-old girl, without history of relevant diseases, that experienced dyspnea and pruritus with wheals starting about ten minutes after beginning any kind of physical exercise. The same symptoms were elicited by emotional stress and hot showers, and were present for the last two years. After ruling out cardiopulmonary diseases and other causes of urticaria, we performed a provocation test (exercise challenge) and the diagnosis of cholinergic urticaria was established. Therapy with ketotifen, an H1 antagonist with mast cell stabilization properties, allowed only a moderate symptom control. Discussion: Cholinergic urticaria may affect greatly the quality of life. Treatment is often difficult, becoming a challenge for the pediatrician.

: cholinergic; histamine H1 antagonist; urticaria.

        · |     · |     · ( pdf )