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Jornal Português de Gastrenterologia

 ISSN 0872-8178

OLIVEIRA, Luís; GORJAO, Ricardo    DEUS, João Ramos de. Whipple’s disease. []. , 17, 2, pp.69-77. ISSN 0872-8178.

The authors review the entity known as Whipple’s disease, describing its epidemiology and clinical presentation, discussing and updating recent advances relevant to its diagnostic and therapeutic management. Whipple’s disease is a rare, chronic bacterial illness, with multisystemic involvement, caused by a gram-positive bacillus, Tropheryma Whipplei, of the Actinobacterias family and Actinomycetes group. Due to its multiform presentation and rarity it is often misdiagnosed and warrants close follow-up to assess therapeutic response.

: Whipple Disease; Tropheryma Whippleii; Infection.

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