VARGAS, Sara et al. Loeys-Dietz Syndrome and pregnancy: two case reports and literature review. []. , 14, 4, pp.263-266.   01--2020. ISSN 1646-5830.

Loeys-Dietz syndrome is a rare autosomal dominant connective tissue disorder characterized by vascular, skeletal, craniofacial and cutaneous abnormalities. During pregnancy, women with this syndrome have an increased risk of aortic aneurysm and dissection, preterm birth, uterine rupture and postpartum hemorrhage. Appropriate preconceptional, pregnancy and postpartum evaluation, counseling and surveillance by a specialized and multidisciplinary team might improve maternal and pregnancy outcomes. We present two cases of pregnant women with this syndrome surveilled at a tertiary high-risk obstetrics center. Both delivered at term without major complications.

: Pregnancy; Cardiovascular Diseases; Loeys-Dietz Syndrome; Pregnancy Complications.

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