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Acta Obstétrica e Ginecológica Portuguesa

 ISSN 1646-5830

SILVA, Ana Filipa; CASTRO, Andreia Cunha; FIGUEIREDO, Carlos José    SANTOS, Emília dos. Postmenopausal hormone replacement therapy and risk of breast and gynecologic cancer. []. , 17, 2, pp.135-150.   30--2023. ISSN 1646-5830.

Hormone Therapy (HT) is the most effective treatment for symptom control during menopause due to hypoestrogenism. Studies that linked HT to the risk of breast cancer led to a decrease in its prescription. This article seeks to review the risk of breast and gynecologic cancer associated with HT use. It is concluded that it’s a safe and effective option in symptomatic menopausal woman up to the age of 60, without contraindications, in the first 10 years post-menopause. The main concern prescribing it is the risk of breast cancer, which is only significant with a prolonged use over 5 years.

: Hormone replacement therapy; Postmenopausal; Genital neoplasms, female; Breast neoplasms; Endometrial neoplasms; Cervical uterine neoplasms; Ovarian neoplasms.

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