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GE-Portuguese Journal of Gastroenterology
versão impressa ISSN 2341-4545
Resumo
LEAL, Tiago et al. Colitis due to Cytomegalovirus and Herpes Simplex Type 2 as a Complication of a First Presentation of Inflammatory Bowel Disease. GE Port J Gastroenterol [online]. 2022, vol.29, n.1, pp.56-60. Epub 19-Jul-2022. ISSN 2341-4545. https://doi.org/10.1159/000514715.
Introduction:
The first presentation of ulcerative colitis may be an acute flare in about 15% of patients, requiring hospital admission. In acute severe steroid-refractory ulcerative colitis, cytomegalovirus (CMV) should be sought because it is a frequent cause of refractory disease. Herpes simplex colitis constitutes a rarer event in ulcerative colitis patients and it is usually associated with immunosuppression.
Case Presentation:
We report a case of a first presentation of ulcerative colitis complicated by CMV and herpes simplex type 2 coinfection. After a long period of systemic corticosteroids, the diagnosis of both CMV and herpes colitis was made. Despite antiviral treatment, colectomy was required due to a contained perforation.
Discussion/Conclusion:
This report highlights the importance of a high degree of suspicion for opportunistic infections in steroid/immunomodulator refractory ulcerative colitis, even in the first flare.
Palavras-chave : Inflammatory bowel disease; Cytomegalovirus; Herpes simplex vírus; Opportunistic infection; Colectomy.