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Revista Portuguesa de Imunoalergologia
versão impressa ISSN 0871-9721
Resumo
FERNANDES, Mara; SOUSA, Filipa e CAMARA, Rita. Alpha-gal syndrome: Two case reports. Rev Port Imunoalergologia [online]. 2021, vol.29, n.1, pp.49-53. Epub 31-Mar-2021. ISSN 0871-9721. https://doi.org/10.32932/rpia.2021.03.053.
Background:
Hypersensitivity to red meat has been increasing and is related to sensitization to galactose‑α‑1, 3‑galactose (alpha‑gal).
Case reports:
The authors describe 2 cases of red meat allergy due to alpha‑gal sensitization. Case A: 47‑year‑old atopic male, with several episodes of generalized urticaria and lip angioedema, 30 minutes to 6 hours after ingestion of red meat. Skin tests were positive to red meat and specific IgE positive for pork, beef and alpha‑gal. Case B: 42‑year old male without any atopic disease, with generalized urticaria and oropharyngeal tightening 6h after pork ingestion (> 10 episodes). Skin tests were positive to pork and specific IgE assay positive for pork, beef and alpha‑gal. After red meat avoidance, no other manifestations were reported.
Palavras-chave : Alpha‑gal; food allergy; red meat..