Linfoma não Hodgkin primário do fígado em doente com hepatite crónica a VHC

 

M. L. Gonçalves¹, I. Rosa¹, I. Medeiros¹, C. Viveiros¹, A. Talhinhas², J. Fernândez Mera³, F. Pina⁴, A. Queiroz¹

 

Resumo

Os autores apresentam o caso de um homem de 43 anos, com dor abdominal e sintomas constitucionais com 3 semanas de evolução, a quem se diagnosticou tumor solido do fígado e infecção crónica a Virus da Hepatite C (VHC). O tumor era um Linfoma não Hodgkin ( LNH) tipo B, primário. O doente foi submetido a quimioterapia e a tratamento para a hepatite crónica C, com boa resposta.

Os autores discutem o caso e apresentam uma revisão da litera-tura sobre a associação VHC e LNH, em particular o LNH primário do fígado, e o eventual papel do virus na génese de linfomas.

 

Summary

The authors present the case of a 43 year old man, with abdominal pain and constitutional symptoms during 3 weeks, in whom was diagnosed a solid liver tumor and chronic hepatitis C. The tumor was a primary cell B non-Hodgkin Lymphoma (LNH). The patient was submitted to chemotherapy and treatment for hepatitis C with a favourable response.

The authors discuss the case and present a review on the VHC and LNH association, the primary hepatic lymphoma in particular, and the possible role of the virus in lymphomagenesis.

 

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Bibliografia

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⁽¹⁾ Unidade de Gastrenterologia do Hospital Espírito Santo, Évora, Portugal

⁽²⁾ Serviço de Imagiologia do Hospital Espírito Santo, Évora, Portugal

⁽³⁾ Serviço de Anatomia Patológica do Hospital Espírito Santo, Évora, Portugal

⁽⁴⁾Unidade de Hematologia do Hospital Espírito Santo, Évora, Portugal

e-mail: lurdesgo@aeiou.pt

 

 

 

Recebido para publicação: 21/01/2005

Aceite para publicação: 27/04/2005