A propósito de um caso de imunodeficiência comum variável – Revisão das hipogamaglobulinemias

 

About a case of common variable immunodeficiency – Revision of hypogammaglobulinemias

 

Alexandra Lopes*

Fernando Barata**

 

Resumo

A imunodeficiência comum variável é uma imunodeficiência primária caracterizada por distúrbios imunológicos heterogéneos, de etiologia desconhecida. As suas manifestações clínicas incluem infecções recorrentes, doenças auto-imunes, hiperplasia linfóide, doenças granulomatosas e neoplasias; pode aparecer em doentes com deficiência de IgA. Os autores apresentam o caso clínico de doente com imunodeficiência comum variável e história de infecções respiratórias de repetição desde os 9 meses, associadas ao aparecimento de bronquiectasias.

Palavras-chave: Imunodeficiência comum variável

 

Abstract

Common variable immunodeficiency is a primary immune deficiency characterized by heterogeneous immunologic disorders of unknown etiology. Its clinical manifestations include recurrent infections, autoimmune diseases, lymphoid hyperplasia, granulomatous diseases and malignancy. It can appear in patients with immunoglobulin A deficiency. The authors report the clinical case of a patient with common variable immunodeficiency and history of respiratory infections from the age of 9 months old, associated with the appearing of bronchiectasis.

Key-words: Common variable immunodeficiency.

 

 

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* Internato Complementar de Medicina Interna

** Assistente Hospitalar Graduado de Pneumologia

* Serviço de Medicina do Centro Hospitalar de Coimbra. Director: Dr. Ricardo Conceição

** Serviço de Pneumologia do Centro Hospitalar de Coimbra (Director: Dr. Rui Pato)

Serviço onde foi realizado o trabalho: Serviço de Pneumologia do Centro Hospitalar de Coimbra

Correspondência:

Drª. Alexandra Lopes, Serviço de Medicina do Centro Hospitalar de Coimbra

Quinta dos Vales,

3040 Coimbra

 

Recebido para publicação/received for publication: 05.03.02

Aceite para publicação/accepted for publication: 06.03.24