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Revista Portuguesa de Pneumologia
versão impressa ISSN 0873-2159
Rev Port Pneumol v.14 n.3 Lisboa jun. 2008
Prevalência e caracterização clínica dos doentes com insuficiência respiratória parcial grave internados numa UCI
Alexandra Borba1 1
Sofia Lourenço 2
Paulo Marcelino 3
Susan Marum 3
Ana Paula Fernandes 3
Resumo
Objectivos: A insuficiência respiratória parcial aguda (IRPA) grave é uma situação comum na prática dos cuidados intensivos, mas os estudos existentes são insuficientes. Com este trabalho pretendeu-se estudar a prevalência e caracterizar clinicamente a população de doentes internados numa UCI que apresentam insuficiência respiratória parcial aguda grave.
Material e métodos: Numa unidade de cuidados intensivos médico-cirúrgica avaliaram-se retrospectivamente os doentes internados durante o ano de 2004.
Resultados: 37,6% dos doentes apresentaram IRPA grave. A análise estatística demonstrou que estes doentes diferiam dos doentes sem IRPA nos tempos de internamento e ventilação, índices de gravidade e mortalidade.
Conclusão: A IRPA é uma situação com elevada prevalência e relevância em cuidados intensivos, mas as características destes doentes estão mal definidas, em parte devido à ausência de critérios claros na sua definição. Para melhor compreender este fenómeno são necessários mais estudos, prospectivos e multicêntricos.
Palavras-chave: Insuficiência respiratória parcial, hipoxemia, cuidados intensivos.
Prevalence and clinical characterisation of patients with severe partial respiratory failure admitted to an intensive care unit
Objective: The authors analysed patients with severe partial respiratory failure (SPRF) admitted to a general Intensive Care Unit (ICU). The prevalence and clinical characteristics of these patients were evaluated.
This work aims to study the rate of and to clinically characterise the patient population admitted to an Intensive Care Unit with acute severe partial respiratory failure.
Material and methods: In 16-bed ICU of a central Hospital in Lisbon, patients admitted in the year 2004 were analysed. Patients with SPRF were recruited form patients with an ICU stay> 24 hours. They were selected according to PaO2 and FiO2 and clinically characterized.
Results: During the study period 472 patients were admitted, and 378 presented an ICU stay> 24 hours and were enrolled. From those, 142 (37.6%) met criteria for SPRF. Of these, 45 (31.7%) a pulmonary aetiology of SPRF was identified. Patients with SRPF were older, had longer ICU stay, and presented higher severity indexes and mortality.
The prevalence of adult respiratory distress syndrome was possible to evaluate in the deceased patients with SPRF (n=52). In these we could find 12 (23%) patients that met criteria for that entity. By multivariate analysis the mortality of patients with SRPF correlated with older age and the presence of circulatory failure (p<0.001).
Conclusions: SPRF is a situation highly prevalent in the ICU studied. To better understand the prevalence of this entity, properly designed studies are needed in order to establish its epidemiology and clinical characteristics.
Key-words: Severe partial respiratory failure, hypoxamia, intensive care unit.
Texto completo disponível apenas em PDF.
Full text only available in PDF format.
Bibliografia / Bibliography
1. Vincent JL, Akça S et al. The epidemiology of acute respiratory failure in critically ill patients. Chest 2002, 121: 1602-9. [ Links ]
2. Bernard GR, Artigas A, Brigham KL et al. Report of the American-European Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Intensive Care Med 1994;20(3):225-32.
3. Lewandowski K. Contributions to the epidemiology of acute respiratory failure. Crit Care 2003; 7(4): 288-291.
4. Roupie E, Lepage E, Wysocki M, Fagon J-Y, Chastre J, Dreyfuss D, Mentec H, Carlet J, Brun-Buisson C, Lemaire F, Brochard L. Prevalence, etiologies and outcome of the acute respiratory distress syndrome among hypoxemic ventilated patients. Intensive Care Medicine 1999; 25:920-9.
5. Flaatten H, Gjerde S, Guttormsen AB, Haugen O, Høivik T, Onarheim H, Aardal S. Outcome after acute respiratory failure is more dependent on dysfunction in other vital organs than on the severity of the respiratory
failure. Critical Care 2003; 7:R72-R77.
6. Schuster DP. The search for objective criteria of ARDS. Intensive Care Med 2007; 33(3): 400-402
7. Schuster DP. What is acute lung injury? What is ARDS? Chest 1995; 107: 1721-6.
8. Luhr OR, Antonsen K, Karlsson M, Aardal S, Thorsteinsson A, Frostell CG, Bonde J and the ARF Study Group. Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark and Iceland. Am J Respir Crit Care Med 1999; 159: 1849-61.
9. Lewandowski K, Metz J, Deutschmann C, Preib H, Kuhlen R, Artigas A, Falke KJ. Incidence, severity and mortality of acute respiratory failure in Berlin, Germany. Am J Respir Crit Care Med 1995; 151: 1121-5.
10. Lobo SM, Lobo FR, Lopes Ferreira F, Bota DP, Melot C, Vincent JL. Initial and delayed onset of acute respiratory failure: factors associated with development and outcome. Anesth Analg 2006; 103 (5): 1219-23.
11. Agarwal R, Aggarwal AN, Gupta D, Behera D, Jindal SK. Etiology and outcomes of pulmonary and extrapulmonary acute lung injury/ARDS in a respiratory ICU in North India. Chest 2006; 130(3): 724-9.
12. Estenssoro E, Dubin A, Laffaire E, Canales H, Sáenz G, Moseinco M, et al. Incidence, clinical course and outcome in 217 patients with acute respiratory distress syndrome. Crit Care Med 2002; 30: 2450-6.
13. Valta P, Uusaro A, Nunes S, Ruokonen E, Takala J. Acute respiratory distress syndrome: frequency, clinical course and costs of care. Crit Care Med 1999; 27: 2367-74.
1 Interna do Internato Complementar de Pneumologia / Resident, specialising in Pulmonology
2 Interna do Internato Complementar de Medicina Interna / Resident, specialising in Internal Medicine
3 Assistente Hospitalar de Medicina Interna, subespecialista em Medicina Intensiva / Consultant, Internal Medicine, sub-specialist in Intensive Medicine
Hospital de Curry Cabral, Unidade de Cuidados Intensivos (Director, Dr. Luís Mourão)
Recebido para publicação/received for publication: 07.07.18
Aceite para publicação/accepted for publication: 08.01.07