Fenómeno de Raynaud

 

Ivone Silva *, Tiago Loureiro **, Isabel Almeida ***, Armando Mansilha ****, Rui Almeida *****, Carlos Vasconcelos ******

*Assistente Hospitalar Graduado do Serviço de Angiologia e Cirurgia Vascular do Hospital Santo António – Centro Hospitalar do Porto; Co-responsável pela Consulta de Grupo de Raynaud; Consulta da Unidade de Imunolgia Clínica

** Interno Complementar do Serviço de Angiologia e Cirurgia Vascular do Hospital Santo António – Centro Hospitalar do Porto

*** Assistente Hospitalar Graduado do Serviço de Medicina do Hospital Santo António – Centro Hospitalar do Porto; Co-responsável pela Consulta de Grupo de Raynaud; Membro da Unidade de Imunologia Clínica

**** MD, PHD, FEBS, Assistente Hospitalar de Angiologia e Cirurgia Vascular, Professor Auxiliar Convidado da Faculdade de Medicina da Universidade do Porto; Secretário Geral da SPACV

***** Chefe de Serviço, Director do Serviço de Angiologia e Cirurgia Vascular do Hospital Santo António – Centro Hospitalar do Porto, Presidente da SPACV

****** MD, PHD, Chefe de Serviço, Responsável da Unidade de Imunologia Clínica – Hospital Santo António– Centro Hospitalar do Porto; Professor Associado Convidado de Clínica Médica do Instituto Biomédicas Abel Salazar

 

|RESUMO|

O Fenómeno de Raynaud (FR) é uma manifestação clínica comum, traduzida por vasoespasmos recorrentes dos dedos, na maioria das vezes provocados pela exposição ao frio ou estímulos emocionais.

Pode ser primário (idiopática) ou secundária a diversas doenças ou condições, incluindo doenças do tecido conjuntivo, como esclerose sistémica.

A patogênese da FR é mal compreendido. Actualmente pensa-se que a lesão endotelial e a disfunção vascular associada podem ser as primeiras alteração patogénicas e responsável pelas complicações vasculares nos doentes com RP.

As alterações funcionais (vasoconstrição) e as mudanças estruturais (proliferação intimal e obstrução dos capilares e artérias), traduzem-se clinicamente como RP e úlceras digitais.

O FR é em muitos casos a primeira manifestação da doença secundária associado e precede as outras manifestações clínicas em anos.

Palavras-chave: Fenómeno de Raynaud

 

Raynaud's Phenomenon

|ABSTRACT|

Raynaud´s Phenomenon (RP) is a common clinical disorder, manifested by recurrent vasospasm of fingers and toes, often triggered by exposure to cold temperatures or emotional stress. It can be primary (idiopathic) or secondary to several diseases or conditions, including connective tissue diseases such as systemic sclerosis. The pathogenesis of RP is poorly understood.

It is generally accepted that endothelial damage and vascular dysfunction may be the earliest pathogenetic alteration and ethological factor responsible for vascular complications in RP patients.

Functional abnormalities (vasoconstriction) and structural changes (intimal proliferation, obstruction) are expressed clinically as RP and digital ulcers. RP is the first manifestation of the secondary associated disease and precedes other clinical manifestations by years.

Key words: Raynaud's Phenomenon

 

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