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Revista Portuguesa de Imunoalergologia

Print version ISSN 0871-9721

Abstract

AUN, Marcelo Vivolo et al. Perioperative anaphylaxis: The brazilian experience. Rev Port Imunoalergologia [online]. 2016, vol.24, n.2, pp.99-106. ISSN 0871-9721.

Perioperative anaphylaxis is a rare hypersensitivity reaction, but it has a rapid onset and is potentially fatal. The true incidence is not well known and varies in accordance with the country from 1:1 250 to 1:13 000 surgeries. It may occur through an allergic (IgE-mediated or not) or non-allergic mechanism, but it is believed that the IgE-mediated reactions are the most common and severe. Any product or drug used in the procedure has the potential to be the cause of a reaction, but neuromuscular blocking agents are the most frequently reported, followed by latex and antibiotics. In this mini-review we discuss some key points of the management of these patients and w present Brazilian data, which suggest that an active search for cases by working together with anesthesiologists could lead to an increase in diagnosis and, therefore, better prevention of future reactions

Keywords : Anaphylaxis; anesthesia; drug allergy; hypersensitivity reactions; IgE; latex; neuromuscular blocking agents; surgery.

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