Abstract

AMARAL, Luís. Biological therapeutics in Immunoallergology. Rev Port Imunoalergologia [online]. 2017, vol.25, n.4, pp.243-248. ISSN 0871-9721.

Allergic diseases affect millions worldwide, and there is growing evidence of an increase in the occurrence of allergic diseases over the past few decades. Current treatments for allergy include corticosteroids to reduce inflammation and allergen immunotherapy (AIT). However, some individuals experience treatment-resistant inflammation or adverse reactions. There is a dire need for new therapeutic approaches for individuals with poorly controlled atopic diseases and to improve the safety and effectiveness of AIT. A better understanding of allergic mechanisms through animal models and clinical trials has unveiled potential targets for new therapies, leading to the development of several biologics to treat allergic diseases

Keywords : Anaphylaxis; anti-IgE; biologics; desensitization; immunotherapy; oral tolerance.

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