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Revista Portuguesa de Imunoalergologia
Print version ISSN 0871-9721
Abstract
PRESA, Ana R.; GARCIA, Sónia; CADINHA, Susana and SOUSA, Maria João. Hypersensitivity reaction to Patent Blue Dye. Rev Port Imunoalergologia [online]. 2023, vol.31, n.2, pp.163-167. Epub June 30, 2023. ISSN 0871-9721. https://doi.org/10.32932/rpia.2023.06.114.
Patent Blue Dye (PBD) is a synthetic blue dye commonly used in medical practice for sentinel lymph node mapping in breast cancer. The authors report the case of a patient with invasive ductal carcinoma of the left breast, who underwent unilateral mastectomy with sentinel lymph node mapping. During surgery, the patient developed violaceous urticaria and mild glottic edema. A hypersensitivity reaction to PBD was confirmed by skin prick tests and methylene blue was identified as a possible alternative dye. This article reinforces the need for greater awareness of the possible hypersensitivity reactions to PBD during surgical procedures.
Keywords : Violaceous urticaria; Patent blue; Breast cancer.