Services on Demand
Journal
Article
Indicators
- Cited by SciELO
- Access statistics
Related links
- Similars in SciELO
Share
Portuguese Journal of Nephrology & Hypertension
Print version ISSN 0872-0169
Abstract
COELHO, Inês et al. Extracorporeal light chains removal - What role does this play in 2020?. Port J Nephrol Hypert [online]. 2020, vol.34, n.4, pp.233-238. ISSN 0872-0169. https://doi.org/10.32932/pjnh.2021.01.103.
Multiple Myeloma (MM) is characterized by a neoplastic proliferation of plasma cell clones producing monoclonal immunoglobulin. Manifestations of the disease are heterogenous and include dialysis-requiring acute kidney injury (AKI) caused mainly by cast nephropathy (CN). It is known that early and rapid decrease in serum free light chains (sFLC) levels is particularly important for renal recovery, which has led to a renewed interest in extracorporeal methods of removal of sFLC. In this review we will discuss the management of light chain CN focusing on extracorporeal light chains removal modalities and their indication.
Keywords : Acute kidney injury; cast nephropathy; dialysis; multiple myeloma; serum free light chains.