Abstract

PORTUGAL, Vanessa et al. Liver disturbances in poorly-controlled type I diabetes mellitus. Nascer e Crescer [online]. 2011, vol.20, n.3, pp.132-134. ISSN 0872-0754.

Type I diabetes mellitus (DM) is a chronic endocrine metabolic disease with a increasing incidence in pediatrics. Some diabetic patients with poor metabolic control may develop hepatomegaly induced by glycogen accumulation in early period. The hepatic glycogenosis is a well recognized complication, which is rarely reported in literature. Cases report: We report a case of a six-year-old boy admitted in hospital with a diabetic ketoacidosis. The second case is a fourteen-year-old girl with diabetes referred to our hospital because of frequent hypoglycemic episodes. The last reported case refers to a seventeen-year-old teenager, who was admitted to hospital due to wide fluctuations in glucose levels. They all developed hepatomegaly and elevated serum transaminases. Full recovery was achieved within four weeks. Conclusion: Hepatic Glycogenosis can be associated with acute restoration from diabetic ketoacidosis and wide fluctuations in both glucose and insulin levels.

Keywords : Type I Diabetes Mellitus; Hepatic glycogenosis; hepatomegaly.

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