Abstract

SOARES, Joana et al. Plasmapheresis in acute disseminated encephalomyelitis associated with anti-MOG antibodies - Two clinical cases. Nascer e Crescer [online]. 2022, vol.31, n.2, pp.156-161.  Epub June 30, 2022. ISSN 0872-0754.  https://doi.org/10.25753/birthgrowthmj.v31.i2.25273.

Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system. ADEM should be suspected when a patient develops multifocal neurologic abnormalities with encephalopathy, especially if occurring after a viral infection or immunization. In this study, the authors describe two cases of ADEM with positive anti-myelin oligodendrocyte glycoprotein (MOG) antibodies requiring hospitalization in a Pediatric Intensive Care Unit and plasmapheresis treatment.

Keywords : acute disseminated encephalomyelitis; demyelinating disease; anti-MOG antibody; neurologic signs.

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