Abstract

AZEVEDO, Soraia  and  CORREIA, Anabela. The Importance of Recanalization in Intracranial Venous Thrombosis and Predictive Factors. Medicina Interna [online]. 2017, vol.24, n.3, pp.197-207. ISSN 0872-671X.  https://doi.org/10.24950/rspmi/9/2017.

Introduction:Cerebral venous thrombosis (CVT) is a rare disease that affects mainly young people. The importance of recanalization is controversial but it is related to residual symptoms/ signs. This study aims to calculate the incidence of CVT, to evaluate the importance of recanalization and to define its predictive factors. Material and Methods:This is a retrospective observational study involving patients with CVT diagnosed between 2004 to 2014 in Braga Hospital. Functional assessment was based on the modified Rankin scale. Recanalization was defined as the presence of venous flow in all vessels, including residual. A descriptive statistical analysis was conducted and used test t Student(t), Mann-Whitney U(U), chi-square(?2) or Fisher’s exact test a binary logistic regression was used for predictive model. It was recognized statistical significance p < 0.05. Results:The incidence of CVT was estimated at 1.82 cases per 100 000 person-years. The recanalization was associated with the functional evaluation at 6 (Fisher’s exact test, p< 0.001,f = 0.605). The obtained regression model included the following predictive variables age, arterial hypertension, dyslipidemia, altered state of consciousness and new residual symptoms/signs. This was statistically significant (?2(5) = 37.43, p < 0.001), with a sensitivity of 90.0% and specificity of 70.8%. New residual symptoms/signs is the best predictor of no recanalization (OR = 33.33). Discussion and Conclusion:The recanalization has an important role in prognosis; it was possible to predict its occurrence based on five variables.

Keywords : Intracranial Thrombosis; Predictive Value of Tests; Prognosis; Treatment Outcome; Venous Thrombosis.

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