METHODS:

We analyzed the prescriptions of carbapenems and quinolones among inpatients between July 1st 2017 and June 30th 2019. The clinician reviewed each prescription and intervened, when necessary, directly with the prescriber. The consumption was calculated following the Nordic Council definition (2018 update) for the daily defined dose.

RESULTS:

In the first year we identified 234 (35.0%) non-conform prescriptions. Recommendations were addressed in 108 cases, of which 83.3% were accepted. The consumption of quinolones and carbapenems was reduced by 18.0% and 8.6%, respectively, relatively to the previous year. In the second year we identified 284 (34.5%) non-conform prescriptions. Recommendations were addressed in 215 cases, of which 94.0% were accepted. The consumption of quinolones and carbapenems was reduced by 55.7% and 10.3%, respectively.

DISCUSSION:

Throughout this period, we found a reduction in the consumption of quinolones and carbapenems and an increase in compliance with the AMSP recommendations, reflecting a better education for prescription. This favors a more adequate use of antimicrobials, with lesser predisposal to the development of resistance.

CONCLUSION:

In our hospital, the AMSP is leading to a reduction in the use of carpabenems and quinolones, with good acceptance of the recommendations by the prescribers.

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