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Medicina Interna
Print version ISSN 0872-671X
Abstract
CUNHA, Joana Gomes da et al. Pneumomediastinum as a Complication of SARS-CoV-2 Infection: Case Series. Medicina Interna [online]. 2023, vol.30, n.4, pp.15-22. Epub Jan 10, 2024. ISSN 0872-671X. https://doi.org/10.24950/rspmi.2062.
Introduction:
Even though pneumomediastinum cases are t frequent, it has been described as a non-negligible complication in patients with SARS-CoV-2 infection. According to the available literature at this moment, development of pneumomediastinum in patients with SARS-CoV-2 infection does not seem to be related to the classic mechanism of pulmonary barotrauma. This work aims to raise awareness of this nosological entity and its pathophysiology.
Methods:
The authors conducted a retrospective study of all COVID-19 cases with pneumomediastinum between January and February 2021 in an Internal Medicine ward at a Central Hospital - analysis of their comorbidities, disease evolution, complications, and a review of the available literature.
Results:
From 400 patients admitted with COVID-19, in 2 months under study, 4 developed pneumomediastinum: all male, aged between 68 and 81 years, with various comorbidities, mainly cardiovascular. All were subjected to non-invasive mechanical ventilation, with three of them additionally subjected to invasive mechanical ventilation. They evolved unfavorably and ended up dying.
Conclusion:
Pneumomediastinum, as a complication of SARS-CoV-2 infection, proved to be very serious, with a negative outcome in all the identified patients. It is important to be aware of predisposing factors, for early diagnosis and timely intervention.
Keywords : COVID-19/complications; Mediastinal Emphysema/etiology..