Abstract

FERREIRA, Rosa et al. Acute hepatitis induced by fosfomycin: A case report and review of the literature. J Port Gastrenterol. [online]. 2012, vol.19, n.5, pp.263-266. ISSN 0872-8178.

Fosfomycin is a broad spectrum antibiotic, belonging to the group of phosphonic acid antibiotics that is active against most urinary tract pathogens. It is an effective and safe antibiotic for the treatment of uncomplicated urinary tract infections, which makes it a frequently used drug in our country in this clinical setting. In general, it is well-tolerated and does not appear to cause serious reactions. Most reactions are gastrointestinal. Hepatotoxicity with this drug has been rarely described.We report a case of acute hepatitis induced by a single 3 g dose of fosfomycin, in a previously healthy female adult.

Keywords : Acute hepatitis; Fosfomycin; 3 g Single dose; Adverse drug effect; Acute cystitis.

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