Abstract

MURINELLO, António et al. Trousseau’s syndrome due to asymptomatic pancreatic adenocarcinoma. J Port Gastrenterol. [online]. 2013, vol.20, n.4, pp.172-176. ISSN 0872-8178.  https://doi.org/10.1016/j.jpg.2012.09.006.

The authors report a case of Trousseau’s syndrome presenting in a previously asymptomatic 58-year-old man diagnosed with pancreatic adenocarcinoma and liver metástases during a workup prompted by migratory venous thrombosis and pulmonary embolism. It was followed by an ischaemic stroke that occurred while the patient was just one day off anticoagulante therapy with low-molecular-weight heparin to allow for liver and pancreatic biopsies. Trousseau’s syndrome is defined by recurrent or migratory venous thrombosis, arterial embolism caused by non-bacterial thrombotic endocarditis, or both, in patients with underlying malignancy. Treatment relies on the lifelong administration of heparin, and its interruption - however brief - may promote new thrombotic events.

Keywords : Trousseau’s syndrome; Migratory thrombophlebitis; Heparin; Occult malignancy; Pancreatic adenocarcinoma.

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