Abstract

PEIXOTO, Lígia et al. Immune thrombocytopenia purpure and celiac disease: Casualty?. J Port Gastrenterol. [online]. 2014, vol.21, n.3, pp.117-120. ISSN 0872-8178.  https://doi.org/10.1016/j.jpg.2014.02.003.

Celiac disease is a relatively common, chronic autoimmune disease, triggered by the environment (gliadin, a gluten compound) in a genetically predisposed patient. Some case reports and small series describe the association between celiac disease and others autoimmune disorders, mainly type 1 diabetes mellitus, autoimmune thyroiditis, autoimmune hepatitis and Sjögren syndrome. In the literature, there are 12 reports of an association between celiac disease e immune thrombocytopenic purpura. We report a case of a 24-years-old woman with celiac disease since childhood, which developed immune thrombocytopenic purpura with the reintroduction of a gluten diet. We propose that the coexistence of these two disorders suggests a common immune mechanism.

Keywords : Immune thrombocytopenia purpura; Celiac disease; Gluten; Autoimmunity.

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