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Revista Portuguesa de Pneumologia
versão impressa ISSN 0873-2159
Resumo
VIDEIRA, Paula Alexandra; BORREGO, Luís Miguel e TRINDADE, Hélder. Asthma genetic factors. Rev Port Pneumol [online]. 2006, vol.12, n.6, pp.683-708. ISSN 0873-2159.
Asthma is a chronic inflammatory airways disease, with a rising prevalence, particularly in childhood, and is considered an important Public Health problem. Its familial transmission is recognised, while the description and identification of the genes implicated in this disease are a challenge. In this revision paper the authors give a comprehensive explanation of the associated genes as well as the laboratorial methods that allow their identification.
Palavras-chave : Asthma; genetic susceptibility; genome wide screen; association studies; pharmacogenetics.