Resumen

CAPUCHINHO-JUNIOR, Geraldo Andrade; DIAS, Ricardo Marques  y  CARVALHO, Sônia Regina da Silva de. One hour effects of salbutamol and formoterol on blood pressure, heart rate and oxygen saturation in asthmatics. Rev Port Pneumol [online]. 2008, vol.14, n.3, pp.353-361. ISSN 0873-2159.

Aim: To analyse systolic (SBP) and diastolic blood pressure (DBP), partial oxygen saturation (SpO₂) and heart rate (HR) disorders for an hour after short and long acting ß₂-agonists. Material and methods: Twenty-four severe persistent asthma Pulmonology outpatients at Hospital Universitário Gaffrée e Guinle were selected. SBP, DBP, SpO₂ and HR values were determined before and after 400 µg of salbutamol and 12 µg of formoterol, on different days, with a minimum interval of 24 hours. Results: All patients showed ventilatory obstruction, as seen by a reduced FEV1/FVC ratio. There was no statistical SBP/DBP/HR difference after bronchodilator agents, but SpO₂ increased with salbutamol. Conclusion: A standard dose of salbutamol and formoterol does not cause haemodynamic disorder.

Palabras clave : Asthma; bronchodilator agents/adverse effects; heart rate; blood pressure; oxygen saturation.

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