Abstract

CONDE, Bebiana; FERNANDES, Ana; CUNHA, Manuel  and  AFONSO, Abel. Immunocytoma IgA: Case report. Rev Port Pneumol [online]. 2009, vol.15, n.1, pp.121-127. ISSN 0873-2159.

Immunocytoma is a non-Hodgkin’s indolent evolution B cell lymphoma. It accounts for approximately 1-3% of non-Hodgkin's limphomas and usually onsets in adults aged over 50 years old. It manifests as lymphadenopathy, splenomegaly, hepatomegaly and lymphcytosis in 15 -30% of cases and is rarely seen with pulmonary involvement. Monocloncal peaks of serum immunoglobulin often occur. These are IgM and rarely IgA. We present as an example a male patient aged 52 years old, with recurrent respiratory infections. Clinical work -up identified an immunocytoma IgA stage IV. Diagnosing an indolent lymphoma, we prophylactic polyspecific human immunoglobulin to treat the respiratory infection. Evidence of lymphoma progression leads us to prescribe combined cyclophosphamide (C), vincristine (V), prednisone (P) e rituximab (R) (CVP-R), which has obtained a partial response over two years.

Keywords : Immunocytoma; non-Hodgkin’s lymphoma; pulmonary involvement.

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