Introduction:

Ozone is considered a potent antimicrobial agent and is therefore used as a complementary therapy for wound healing and pain reduction. However, this subject is still little empirically studied.

Objetive:

To analyse the therapeutic capacity of ozone therapy as an adjuvant in wound healing and pain reduction.

Methods:

This was an exploratory, cross-sectional, retrospective, and descriptive study. Data analysis was based on descriptive and inferential statistics using the Mann-Whitney and Friedman tests (continuous data) and the Chi-square/Fisher test (dichotomous or ordinal data).

Results:

Twenty people were included, mostly females (55%) and with a mean age of 61.9 years (±16.7). A more aggravated state of healing and higher levels of initial pain were associated to non-healing (p=0.02; p=0.03, respectively). Regarding the time evolution of wound healing and pain levels (baseline, 1st month, 2nd month and 3rd month) a gradual reduction of values was observed, which reflects a significant improvement of healing and pain reduction. Healing did not occur in only 35% (n=7) of the cases.

Conclusion:

Ozone therapy improved wound healing and reduced the associated pain levels. However, given the small sample size, it is necessary to replicate the study in larger samples and with diversified nosological entities to validate the benefits of this therapeutic intervention.

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