Abstract

BUENO, Andressa Aline Bernardo et al. Patient safety: potential drug-drug interactions caused by the overlapping of medications agreed by the nurse. Rev. Enf. Ref. [online]. 2020, vol.serV, n.3, pp.1-8. ISSN 0874-0283.  https://doi.org/10.12707/RV20038.

Background: Hospital drug therapy has the potential for incidents, thus it is necessary to identify situations that may compromise patient safety. Objective: To investigate potential drug-drug interactions caused by the overlapping of medications planned by nurses in the patients' prescriptions at a hospital inpatient unit. Methodology: Descriptive, cross-sectional study of documentary analysis with a quantitative approach, of 260 prescriptions for adult patients. Potential drug- interactions were identified using the Drug Interaction Checker (Medscape^®). Results: A total of 3066 doses were analyzed, with a concentration of 4 schedules, showing an institutional standardization of schedules. The omission error rate was 5.44%. Drug-drug interactions of moderate severity were more frequent, especially lopinavir/clonazepam and diazepam/tramadol combinations. Conclusion: Omission errors and interactions can be minimized with tools to support clinical decision and reconfiguration of the work process.

Keywords : patient safety; medication errors; drug interactions; medication systems; hospital; nursing.

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