Abstract

VILELA, Fernanda; MARTINS, Rita; EDRAL, Ana  and  PACHECO, Amália. Doença de McArdle e Gravidez. Acta Obstet Ginecol Port [online]. 2019, vol.13, n.1, pp.47-49. ISSN 1646-5830.

McArdle disease is a hereditary skeletal muscle disorder caused by myophosphorylase deficiency. This syndrome is characterized by exercise intolerance, fatigue, myalgias, cramps, and weakness. It is a rare disease, with few reported cases of pregnancy in women with this condition. Despite not having specific treatment, adequate physical activity can improve patient symptoms and prevent acute rhabdomyolysis. We present a case of a pregnant woman with McArdle disease. During pregnancy there was an improvement of exercise tolerance and creatine kinase levels. This case report illustrates our experience regarding the management of pregnancy and labour in women with McArdle disease.

Keywords : Pregnancy; McArdle; Glycogen.

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