Abstract

MIRANDA, Cláudia; COSTA, Sofia; COELHO, Diana  and  DANTAS, Sofia. Pregnancy after intracytoplasmic sperm injection in couples with Kartagener syndrome. Acta Obstet Ginecol Port [online]. 2023, vol.17, n.1, pp.67-71.  Epub Mar 31, 2023. ISSN 1646-5830.

Primary ciliary dyskinesia PCD is characterized by congenital impairment of mucociliary clearance. Kartagener syndrome KS is a rare subtype of PCD defined by the triad: bronchiectasis, chronic sinusitis and situs inversus. Male patients with KS have almost no spontaneous pregnancies due to complete immotility of their spermatozoa. Intracytoplasmic sperm injection ICSI is considered the treatment of choice despite showing lower fertilization rates in these patients. Different tests for assortment and selection of viable immotile spermatozoa are described. We present two cases of KS where pregnancy was achieved with ICSI using different methods of spermatozoa selection.

Keywords : Reproductive techniques, Assisted; Kartagener syndrome; Sperm injections, Intracytoplasmic; Ciliary motility disorders; Asthenozoospermia.

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