Abstract

TEIXEIRA, Carolynne Martins  and  MELO, Marcela Melquiades de. RELATIONSHIP OF INTESTINAL MICROBIOTES AND BIOACTIVE COMPOUNDS IN MODULATION OF OBESITY-RELATED GENES. Acta Port Nutr [online]. 2021, n.25, pp.54-57.  Epub Nov 03, 2021. ISSN 2183-5985.  https://doi.org/10.21011/apn.2021.2510.

The advancement of omic sciences has allowed the identification of genetic variants and epigenetic mechanisms involved in the outcome of obesity and nutritional factors that modulate this process. In addition to genetic polymorphisms, the composition of the intestinal microbiota has been shown to be related to genetic variants associated with adipogenesis. Therefore, the aim of this study was to evaluate the relationship between the intestinal microbiota and the bioactive compounds in food in the modulation of genes related to obesity, highlighting the main epigenetic mechanisms.

Keywords : Epigenetics; Nutrients; Nutrigenomics; Gut Microbiota; Obesity.

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