Abstract

ALMEIDA, Ana Catarina Vieira; SALVADO, Heidi de Jesus Faísca  and  PEREIRA, Liliana Dias. Manitol extravasation: nursing case report. Revista Onconews [online]. 2020, n.41, pp.18-24.  Epub Dec 01, 2020. ISSN 1646-7868.  https://doi.org/10.31877/on.2020.41.02.

Several drugs have the potential to cause tissue damage if extravasation occurs. The severity of extravasation and the size of the lesion are dependent on a number of factors such as the dose of the drug, its concentration, place of administration and length of drug exposure. Prevention is the most effective form of management in case of an extravasation/ leakage. If an overflow occurs it is crucial to adopt a suitable set of measures/protocol not only to manage the overflow but to minimize the resulting damage. The most frequently reported extravasation lesions unrelated to chemotherapy administration are caused by hyperosmolar solutions and vasopressor agents. Hyaluronidase is the antidote to hyperosmolar drugs and its administration is important in preventing tissue damage due to extravasation.

Keywords : Vesicant extravasation; mannitol; nursing; hyaluronidase.

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