Abstract

MONTEZINHO, Sara; OLIVEIRA, Miguel  and  ALVES, Manuela. Severe Thrombocytopenia Caused by Piperacillin/Tazobactam: A Case Report. Gaz Med [online]. 2021, vol.8, n.1, pp.57-60.  Epub May 17, 2021. ISSN 2183-8135.  https://doi.org/10.29315/gm.v8i1.382.

Thrombocytopenia is a recognized side effect of various medications, beverages, foods, and herbal remedies. Piperacillin/tazobactam is a beta-lactam/beta-lactamase inhibitor combination with a broad spectrum of antibacterial activity, associated with hematologic adverse such as reversible neutropenia, but Coombs-positive hemolytic anemia and thrombocytopenia are also reported. We report a case of a 73-year-old male patient with severe piperacillin/tazobactam induced thrombocytopenia later confirmed due to re-exposure to the drug.

Keywords : Piperacillin, Tazobactam Drug Combination/adverse effects; Thrombocytopenia/chemically induced.

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