Enterocolite Neutropénica em doente transplantado hepático

A. Cruz, S. C. Lima, S. Barroso, J. Cotter *

 

Resumo

A enterocolite neutropénica é um processo necrotizante, rapidamente progressivo e potencialmente fatal que envolve o cego, íleon terminal e cólon ascendente.

Mais frequentemente descrita em associação com quimioterapia para neoplasias hematológicas, tem tido um interesse crescente devido à associação com novos esquemas de quimioterapia intensivos para neoplasias sólidas.

Cursa com sintomatologia gastrointestinal inespecífica, sendo a precocidade no diagnóstico e na instituição terapêutica essenciais para a redução da taxa de mortalidade.

Apresenta-se, pela particularidade de ocorrer num doente transplantado hepático, o caso clínico de um doente do sexo masculino, de 54 anos de idade, com o diagnóstico de enterocolite neutropénica tratado com sucesso com terapêutica médica conservadora.

 

 

Summary

Neutropenic enterocolitis is a rapidly progressive and potentially fatal necrotizing process involving the terminal ileum, cecum and ascending colon. Previously it has been described in association with chemotherapy for hematological diseases.

Recently, it has also been observed after several chemotherapy regimens for solid tumors.

It is characterized by non-specific gastrointestinal symptoms. The early diagnosis and treatment are essential to reduce the mortality rate.

We present the unusual case of a 54 year old male patient submitted to liver transplantation who developed neutropenic enterocolitis, which was successfully treated with conservative medical management.

 

 

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Bibliografia

 

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* Centro Hospitalar do Alto Ave – Guimarães (Serviço de Gastrenterologia), Portugal.

 

Correspondência:

Dr. José Cotter

Centro Hospitalar do Alto Ave – Guimarães

Serviço de Gastrenterologia

Rua dos Cutileiros – Creixomil

4810-005 Guimarães

e-mail: jcotter@hguimaraes.min-saude.pt

 

Recebido para publicação: 18/05/2007

Aceite para publicação: 12/12/2007