Gânglio inguinal como única evidência de cancro progressivo do pulmão

 

 Zafer Kocak ¹

Mert Saynak ¹

Fulya Oz-Puyan ²

Irfan Cicin ³

Rusen Cosar-Alas ¹

Murat Caloglu ¹

Gundeniz Altiay ⁴

Sernaz Uzunoglu ³

 

 

Resumo

Os tumores que metastizam para os gânglios inguinais têm frequentemente origem nos órgãos genitais e reprodutores, na pele, no recto ou ânus, ou na bexiga1,2.

Há, no entanto, algumas descrições de casos raros de metástases inguinais de tumores localizados acima do diafragma2-5, e apenas três destes apresentavam uma metástase inguinal reconhecida antes da morte. Estes casos estão detalhadamente descritos na literatura médica de língua inglesa3-5. Os tumores primários destes casos eram mesotelioma maligno e carcinomas do conduto salivar e da mama. Descrevemos um caso de carcinoma do pulmão que metastizou para gânglio inguinal, como única evidência de cancro do pulmão progressivo.

Palavras-chave: Carcinoma do pulmão de não pequenas células, gânglio inguinal, metástase, progressão da doença.

 

 

Inguinal lymph node as the only evidence of progressive lung cancer

Abstact

Tumours that metastasise to groin nodes most frequently originate in genital and reproductive organs, skin, rectum or anus, or urinary bladder1,2.

However, rare cases of inguinal metastases from tumours above the diaphragm have been reported2-5 and only three of them had an inguinal metastasis which was recognised antemortem and reported in detail in the English medical literature3-5. The primary tumours of these cases were malignant mesothelioma, salivary duct and breast carcinoma. In this paper, we report a case of carcinoma of the lung metastatic to an inguinal lymph node as the only evidence of progressive lung cancer.

Key -words: Non-small cell lung carcinoma, inguinal lymph node, metastasis, disease progression.

 

 

Texto completo disponível apenas em PDF.

Full text only available in PDF format.

 

 

Bibliography

1. Guarischi A, Keane TJ, Elhakim T. Metastatic inguinal nodes from an unknown primary neoplasm. A review of 56 cases. Cancer 1987; 59:572-7.        [ Links ]

2. Zaren HA, Copelan EM 3rd. Inguinal node metastases. Cancer 1978; 41:919-23.

3. King JA, Listinsky CM, Tucker JA. An intriguing case: malignant mesothelioma presenting as inguinal lymph node metastases. Ultrastruct Pathol 2004; 28:109-13.

4. Bhalla R, Parker DC, Tadros TS. Salivary duct carcinoma metastatic to inguinal lymph node: a case report of salivary duct carcinoma with distant metastasis diagnosed by fine-needle aspiration. Diagn Cytopathol 2006; 34:41-4.

5. Baba M, Tatsuta M, Miya A, Ishida H, Masutani S, Kawasaki T, et al. A case of breast cancer diagnosed by inguinal lymph node metastasis. Breast Cancer 2000; 7:173-5.

6. Quint LE, Tummala S, Brisson LJ, Francis IR, Krupnick AS, Kazerooni EA, et al. Distribution of distant metastases from newly diagnosed non-small cell lung cancer. Ann Thorac Surg 1996; 62:246-50.

7. Riquet M, Le Pimpec-Barthes F, Danel C. Axillary lymph node metastases from bronchogenic carcinoma. Ann Thorac Surg 1998; 66:920-2.

8. Schrump DS, Altorki NK, Henschke CL, Carter D, Turrisi AT, Gutierrez ME. Non-small cell lung cancer. In: DeVita VT, Hellman S, Rosenberg SA (eds) Cancer Principles & Practice of Oncology, 7th edn. Philadelphia. PA: 2004; 753-810.

9. Zamecnik J, Kodet R. Value of thyroid transcription factor-1 and surfactant apoprotein A in the differential diagnosis of pulmonary carcinomas: a study of 109 cases. Virchows Arch 2002; 440:353-61.

10. Rossi G, et al. TTF-1, Cytokeratin 7, 34-Beta-E12, and CD56/NCAM immunostaining in the subclassification of large cell carcinomas of the lung. Am J Clin Pathol 2004; 122:884-93.

11. Ordonez NG. The diagnostic utility of immunohistochemistry indistinguishing between epithelioid mesotheliomas and squamous carcinomas of the lung: A comparative study. Mod Pathol 2006; 19:417-28.

 

 

1 Departments of Radiation Oncology

2 Pathology

3 Medical Oncology

4 Chest Disaese

Trakya University Hospital, Edirne, Turkey

Correspondence:

Mert Saynak, MD.

Trakya University Hospital, Department of Radiation Oncology,

Edirne 22030, Turkey

Tel: + 90 284 2361778

Fax: + 90 284 2361074

E-mail: mertsaynak@gmail.com

 

Recebido para publicação/received for publication: 07.04.03

Aceite para publicação/accepted for publication: 08.05.26