<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0871-3413</journal-id>
<journal-title><![CDATA[Arquivos de Medicina]]></journal-title>
<abbrev-journal-title><![CDATA[Arq Med]]></abbrev-journal-title>
<issn>0871-3413</issn>
<publisher>
<publisher-name><![CDATA[ArquiMed - Edições Científicas AEFMUP ]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0871-34132007000100004</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Cardiovascular risk factors in adolescence]]></article-title>
<article-title xml:lang="pt"><![CDATA[Factores de risco cardiovasculares na adolescência]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramos]]></surname>
<given-names><![CDATA[Elisabete]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Universidade do Porto Faculdade de Medicina Serviço de Higiene e Epidemiologia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>01</month>
<year>2007</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>01</month>
<year>2007</year>
</pub-date>
<volume>21</volume>
<numero>1</numero>
<fpage>25</fpage>
<lpage>35</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S0871-34132007000100004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S0871-34132007000100004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S0871-34132007000100004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[The present review will examine the relationships among behavioural and biological cardiovascular risk factors during adolescence and cardiovascular disease later in adult life. A consistent finding is the co-occurrence of behavioural cardiovascular risk factors such as smoking, alcohol consumption, unhealthy diets and physical inactivity. Although there are no consensual criteria to define adolescence overweight, it is the most prevalent cardiovascular risk factor representing an increasingly important health problem, and the increase in the prevalence overweight, among younger age groups, is likely to have effect on others biological cardiovascular risk factors during adolescence and long-term implications for cardiovascular disease. A cluster of risk factors that includes overweight, hypertension, dyslipidemia and insulin resistance was described in children and adolescents, leading to the hypothesis that the clustering process begins early in life and persists in adulthood.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Esta revisão investiga a relação entre factores de risco cardiovasculares, comportamentais e biológicos, na adolescência e a ocorrência de doença cardiovascular na vida adulta. Factores de risco comportamentais, como hábitos tabágicos, consumo de bebidas alcoólicas, níveis baixos de actividade física e uma ingestão alimentar habitualmente associada a risco de doença, tendem a agregar-se. Apesar de não existir um critério consensual para a definição de excesso de peso em adolescentes, é o factor de risco mais prevalente neste grupo etário, e representa um problema crescente com impacto não só na mortalidade e morbilidade na vida adulta, mas também em outros factores de risco biológicos durante a adolescência. Nos adolescentes já se observa a agregação de factores de risco como o excesso de peso, hipertensão arterial, dislipidemia e resistência à insulina, o que suporta a hipótese que esta agregação se inicia em fases precoces da vida.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[cardiovascular disease]]></kwd>
<kwd lng="en"><![CDATA[adolescent]]></kwd>
<kwd lng="en"><![CDATA[risk factors]]></kwd>
<kwd lng="en"><![CDATA[child]]></kwd>
<kwd lng="pt"><![CDATA[doença cardiovascular]]></kwd>
<kwd lng="pt"><![CDATA[adolescente]]></kwd>
<kwd lng="pt"><![CDATA[factores de risco]]></kwd>
<kwd lng="pt"><![CDATA[criança]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <p   align="justify" ><B>Cardiovascular Risk Factors in Adolescence</B> </p >    <P   align="justify" >Elisabete Ramos </P >     <P   >Servi&ccedil;o de Higiene e Epidemiologia, Faculdade de Medicina da Universidade    do Porto </P >     <P   ><b>Abstract</b></P >        <P   >The present review will examine the relationships among behavioural and biological    cardiovascular risk factors during adolescence and cardiovascular disease later    in adult life. A consistent finding is the co-occurrence of behavioural cardiovascular    risk factors such as smoking, alcohol consumption, unhealthy diets and physical    inactivity. Although there are no consensual criteria to define adolescence    overweight, it is the most prevalent cardiovascular risk factor representing    an increasingly important health problem, and the increase in the prevalence    overweight, among younger age groups, is likely to have effect on others biological    cardiovascular risk factors during adolescence and long-term implications for    cardiovascular disease. A cluster of risk factors that includes overweight,    hypertension, dyslipidemia and insulin resistance was described in children    and adolescents, leading to the hypothesis that the clustering process begins    early in life and persists in adulthood. </P >        <P   ><B>Key-words</B>: cardiovascular disease; adolescent; risk factors; child</P >     <P   >&nbsp;</P >     <P   ><b>Resumo</b></P >     <P   ><b>Factores de Risco Cardiovasculares na Adolesc&ecirc;ncia</b></P >     <P   >Esta revis&atilde;o investiga a rela&ccedil;&atilde;o entre factores de risco    cardiovasculares, comportamentais e biol&oacute;gicos, na adolesc&ecirc;ncia    e a ocorr&ecirc;ncia de doen&ccedil;a cardiovascular na vida adulta. Factores    de risco comportamentais, como h&aacute;bitos tab&aacute;gicos, consumo de bebidas    alco&oacute;licas, n&iacute;veis baixos de actividade f&iacute;sica e uma ingest&atilde;o    alimentar habitualmente associada a risco de doen&ccedil;a, tendem a agregar-se.    Apesar de n&atilde;o existir um crit&eacute;rio consensual para a defini&ccedil;&atilde;o    de excesso de peso em adolescentes, &eacute; o factor de risco mais prevalente    neste grupo et&aacute;rio, e representa um problema crescente com impacto n&atilde;o    s&oacute; na mortalidade e morbilidade na vida adulta, mas tamb&eacute;m em    outros factores de risco biol&oacute;gicos durante a adolesc&ecirc;ncia. Nos    adolescentes j&aacute; se observa a agrega&ccedil;&atilde;o de factores de risco    como o excesso de peso, hipertens&atilde;o arterial, dislipidemia e resist&ecirc;ncia    &agrave; insulina, o que suporta a hip&oacute;tese que esta agrega&ccedil;&atilde;o    se inicia em fases precoces da vida. </P >     ]]></body>
<body><![CDATA[<P   ><b>Palavras-chave</b>: doen&ccedil;a cardiovascular; adolescente; factores    de risco; crian&ccedil;a</P >     <P   >&nbsp;</P >     <P   >Texto completo dispon&iacute;vel apenas em PDF.</P >     <p>Full text only available in PDF format.</p>     <P   >&nbsp;</P >          <p   align="justify"><B>REFERENCES</B> </p >     <P   align="justify" >1 -World Health Organization, the United Nations Population Fund and the United    Nations Children&rsquo;s Fund Jointly Convened a Study Group on Programming    for Adolescent Health. Action for Adolescent Health. Towards a Common Agenda.    Recommendations from a Joint Study Group. [Cited 2005 Oct]. Available From:    url <a href="http://www.who.int/child-adolescent-health/new_publications/adh/who_frh_adh_97.9_en.pdf" target="_blank">http://www.who.int/child-adolescent-health/new_publications/adh/who_frh_adh_97.9_en.pdf</a></P >     <P   align="justify" >2 - Instituto Nacional de Estat&iacute;stica. Recenseamento da Popula&ccedil;&atilde;o    e da Habita&ccedil;&atilde;o (Portugal) - Censos 2001. Lisboa: Instituto Nacional    de Estat&iacute;stica; 2003. </P >     <!-- ref --><P   align="justify" >3 - Steinberg L. Cognitive and Affective Development in Adolescence. Trends Cogn    Sci 2005;9:69-74. </P >     &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000021&pid=S0871-3413200700010000400001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><P   align="justify" >4 - Cameron N, Demerath EW. Critical Periods in Human Growth and Their Relationship    to Diseases of Aging. Am J Phys Anthropol 2002;suppl 35:159-84. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >5 - World Health Organization. World Report on Violence and Health. 2002. [Cited    2006 Jan]. Available From: url <a href="http://www.who.int/violence_injury_prevention/violence/world_report/en/full_en.pdfs" target="_blank">http://www.who.int/violence_injury_prevention/violence/world_report/en/full_en.pdf</a></P >     <P   align="justify" >6 - Direc&ccedil;&atilde;o de Servi&ccedil;os de Informa&ccedil;&atilde;o e An&aacute;lise.    Divis&atilde;o de Epidemiologia. Risco de Morrer rm Portugal, 2001. Lisboa:    Direc&ccedil;&atilde;o-Geral da Sa&uacute;de; 2003. [Cited 2005 Oct]. Available    From: url <a href="http://www.dgs.pt/" target="_blank">http://www.dgs.pt/upload/membro.id/    ficheiros/I005964.pdf</a></P >     <P   align="justify" >7 - World Health Organization. The World Health Report 2002. Reducing Risks,    Promoting Healthy Life. World Health Organization: Geneva; 2002. Available From:    url <a href="http://www.who.int/whr/2002/en/whr02_en.pdf" target="_blank">http://www.who.int/whr/2002/en/whr02_en.pdf</a></P >     <P   align="justify" >8 - Powles JW, Zatonski W, Vander Hoorn S, Ezzati M. The Contribution of Leading    Diseases and Risk Factors to Excess Losses of Healthy Life in Eastern Europe:    Burden of Disease Study. BMC Public Health 2005;5:116. </P >     <P   align="justify" >9 - Rodgers A, EzzatiI M, Vander Hoorn S, Lopez AD, Lin RB, Murray CJ. Distribution    of Major Health Risks: Findings from the Global Burden of Disease Study. PLoS    Med 2004;1:e27. </P >     <P   align="justify" >10 - Berenson GS, Srinivasan SR, Bao W, Newman WP, Tracy RE, Wattigney WA. Association    between Multiple Cardiovascular Risk Factors and Atherosclerosis in Children    and Young Adults. The Bogalusa Heart Study. N Engl J Med 1998;338:1650-6. </P >     <P   align="justify" >11 - Napoli C, D&rsquo;Armiento FP, Mancini FP, et al. Fatty Streak Formation    Occurs in Human Fetal Aortas and Is Greatly Enhanced by Maternal Hypercholesterolemia.    Intimal Accumulation of Low Density Lipoprotein and Its Oxidation Precede Monocyte    Recruitment into Early Atherosclerotic Lesions. J Clin Invest 1997;100:2680-90.  </P >     <P   align="justify" >12 - Frost R. Cardiovascular Risk Modification in the College Student: Knowledge,    Attitudes, and Behaviors. J Gen Intern Med 1992;7:317-20. </P >     <P   align="justify" >13 - Smalley SE, Wittler RR, Oliverson RH. Adolescent Assessment of Cardiovascular    Heart Disease Risk Factor Attitudes and Habits. J Adolesc Health 2004;35:374-9.  </P >     <P   align="justify" >14 -World Health Organization. Overview of Child and Adolescent Health. Adolescent    Health and Development. [Cited 2005 Oct]. Available From: url <a href="http://www.who.int/child-adolescent-health/overview/ahd/adh_sheer.htm" target="_blank">http://www.who.int/child-adolescent-health/overview/ahd/adh_sheer.htm</a></P >     ]]></body>
<body><![CDATA[<P   align="justify" >15 - Haymann LL, Williams CL, Daniels SR, et al. Cardiovascular Health Promotion    in the Schools: A Statement for Health and Education Professionals and Child    Health Advocates from the Committee on Atherosclerosis, Hypertension, and Obesity    in Youth (Ahoy) of the Council on Cardiovascular Disease in the Young, American    Heart Association. Circulation 2004;110:2266-75. </P >     <P   align="justify" >16 - McCarron P, Smith GD, Okasha M, Mcewen J. Smoking in Adolescence and Young    Adulthood and Mortality in Later Life: Prospective Observational Study. J Epidemiol    Community Health 2001;55:334-5. </P >     <P   align="justify" >17 - Howard G, Wagenknecht LE, Burke GL, et al. Cigarette Smoking and Progression    of Atherosclerosis: The Atherosclerosis Risk in Communities (Aric) Study. JAMA    1998; 279:119-24. </P >     <P   align="justify" >18 - Relationship of Atherosclerosis in Young Men to Serum Lipoprotein Cholesterol    Concentrations and Smoking. A Preliminary Report from the Pathobiological Determinants    of Atherosclerosis in Youth (Pday) Research Group. JAMA 1990;264:3018-24. </P >     <P   align="justify" >19 - Fraga S, Sousa S, Santos AC, et al. Tabagismo em Portugal. Arq Med 2005;19:207-29.  </P >     <P   align="justify" >20 - Santos AC, Barros H. Smoking Patterns in a Community Sample of Portuguese    Adults, 1999-2000. Prev Med 2004; 38:114-9. </P >     <P   align="justify" >21 - Fraga S, Ramos E, Barros H. [Smoking and Its Associated Factors in Portuguese    Adolescent Students]. Revista de Sa&uacute;de P&uacute;blica 2006;40:620-6.  </P >     <P   align="justify" >22 -Vitoria PD, Kremers SP, Mudde AN, Pais-Clemente M, De Vries H. Psychosocial Factors Related with Smoking Behaviour in Portuguese Adolescents. Eur J Cancer Prev 2006;15:531-40. </P >     <P   align="justify" >23 - Instituto Nacional de Estat&iacute;stica. Destaque do Ine: Dia do N&atilde;o    Fumador. Inqu&eacute;rito aos Or&ccedil;amentos Familiares 2000 - Despesas com    Tabaco. Instituto Nacional de Estat&iacute;stica2002. [Cited 2005 Sept]. Available    From: url <a href="http://www.ine.pt/" target="_blank">http://www.ine.pt/</a></P >     <P   align="justify" >24 - Audrain-McGovern J, Rodriguez D, Tercyak KP, Cuevas J, Rodgers K, Patterson    F: Identifying and Characterizing Adolescent Smoking Trajectories. Cancer Epidemiol    Bio-markers Prev 2004;13:2023-34. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >25 - Donato F, Assaneli D, Chiesa R, Poeta ML, Tomasoni V, Turla C. Cigarette    Smoking and Sports Participation in Adolescents: A Cross-Sectional Survey among    High School Students in Italy. Subst Use Misuse 1997;32:1555-72. </P >     <P   align="justify" >26 - Holmen TL, Barrett-Connor E, Clausen J, Holmen J, Bjermer L. Physical Exercise,    Sports, and Lung Function in Smok-ing Versus Nonsmoking Adolescents. Eur Respir    J 2002; 19:8-15. </P >     <P   align="justify" >27 - Andersen A, Due P, Holstein BE, Iversen L. Tracking Drinking Behaviour from    Age 15-19 Years. Addiction 2003;98:1505-11. </P >     <P   align="justify" >28 - Masterman PW, Kelly AB. Reaching Adolescents Who Drink Harmfully: Fitting    Intervention to Developmental Reality. J Subst Abuse Treat 2003;24:347-55. </P >     <P   align="justify" >29 - Marques-Vidal P, Dias CM. Trends and Determinants of Alcohol Consumption    in Portugal: Results from the National Health Surveys 1995 to 1996 and 1998    to 1999. Alcohol Clin Exp Res 2005;29:89-97. </P >     <P   align="justify" >30 - Wetzels JJ, Kremers SP, Vitoria PD, De Vries H. The Alcohol-Tobacco Relationship:    A Prospective Study among Adolescents in Six European Countries. Addiction 2003;98:1755-63.  </P >     <P   align="justify" >31 - Ellickson PL, Hays RD, Bell RM. Stepping through the Drug Use Sequence:    Longitudinal Scalogram Analysis of Initiation and Regular Use. J Abnormal Psychol    1992;101:441-51. </P >     <P   align="justify" >32 - Jackson KM, Sher KJ, Cooper ML, Wood PK. Adolescent Alcohol and Tobacco    Use: Onset, Persistence and Trajectories of Use across Two Samples. Addiction    2002;97:517-31. </P >     <P   align="justify" >33 - Adrados JL. The Influence of Family, School, and Peers on Adolescent Drug    Misuse. Int J Addict 1995;30:1407-23. </P >     <P   align="justify" >34 - Duncan SC, Duncan TE, Hops H. Progressions of Alcohol, Cigarette, and Marijuana    Use in Adolescence. J Behav Med 1998;21:375-88. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >35 - Lewinsohn PM, Rohde P, Brown RA. Level of Current and Past Adolescent Cigarette    Smoking as Predictors of Future Substance Use Disorders in Young Adulthood.    Addiction 1999;94:913-21. </P >     <P   align="justify" >36 - McMillen IC, Robinson JS. Developmental Origins of the Metabolic Syndrome:    Prediction, Plasticity, and Programming. Physiol Rev 2005;85:571-633. </P >     <P   align="justify" >37 - Barker DJ. The Developmental Origins of Chronic Adult Disease. Acta Paediatr    Suppl 2004;93:26-33. </P >     <P   align="justify" >38 - Ness AR, Maynard M, FrankelL S, et al. Diet in Childhood and Adult Cardiovascular    and All Cause Mortality: The Boyd Orr Cohort. Heart 2005;91:894-8. </P >     <P   align="justify" >39 - Barlow SE, Dietz WH. Obesity Evaluation and Treatment: Expert Committee    Recommendations. The Maternal and Child Health Bureau, Health Resources and    Services Administration and the Department of Health and Human Services. Pediatrics    1998;102:E29. </P >     <P   align="justify" >40 - Committee on School health. Soft Drinks in Schools. Pediatrics 2004;113:152-4.  </P >     <P   align="justify" >41 - Munoz KA, Krebs-Smith SM, Ballard-Barbash R, Cleveland LE. Food Intakes    of Us Children and Adolescents Compared with Recommendations. Pediatrics 1997;100:    323-9. </P >     <P   align="justify" >42 - Giddings SS, Dennison BA, Birch LL, et al. Dietary Recommendations for Children    and Adolescents: A Guide for Practitioners: Consensus Statement from the American    Heart Association. Circulation 2005;112:2061-75. </P >     <P   align="justify" >43 - Vartanian LR, Schwartz MB, Brownell KD. Effects of Soft Drink Consumption    on Nutrition and Health: A Systematic Review and Meta-Analysis. Am J Public    Health 2007;97:667-75. </P >     <P   align="justify" >44 - Krebs-Smith SM, Cook A, Subar AF, Cleveland L, Friday J, Kahle LL. Fruit    and Vegetable Intakes of Children and Adolescents in the United States. Arch    Pediatr Adolesc Med 1996;150:81-6. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >45 - Neumark-Sztainer D, Story M, Hannan PJ, Croll J. Overweight Status and Eating    Patterns among Adolescents: Where Do Youths Stand in Comparison with the Healthy    People 2010 Objectives? Am J Public Health 2002;92:844-1. </P >     <P   align="justify" >46 - Larson NI, Neumark-Sztainer D, Hannan PJ, Story M. Trends in Adolescent    Fruit and Vegetable Consumption, 1999-2004: Project Eat. Am J Prev Med 2007;32:147-50.  </P >     <P   align="justify" >47 - Maynard M, Gunnell D, Emmett P, Frankel S, Davey Smith G. Fruit, Vegetables,    and Antioxidants in Childhood andRisk of Adult Cancer: The Boyd Orr Cohort.    J Epidemiol Community Health 2003;57:218-25. </P >     <P   align="justify" >48 - Bertheke Post G, De Vente W, Kemper HC, Twisk JW. Longitudinal Trends in    and Tracking of Energy and Nutrient Intake over 20 Years in a Dutch Cohort of    Men and Women between 13 and 33 Years of Age: The Amsterdam Growth and Health    Longitudinal Study. Br J Nutr 2001;85:375-85. </P >     <P   align="justify" >49 - Lien N, Lytle LA, Klepp KI. Stability in Consumption of Fruit, Vegetables,    and Sugary Foods in a Cohort from Age 14 to Age 21. Prev Med 2001;33:217-26.  </P >     <P   align="justify" >50 - Dunn JE, Liu K, Greenland P, Hilner JE, Jacobs DR, JR.: Seven-Year Tracking    of Dietary Factors in Young Adults: The Cardia Study. Am J Prev Med 2000;18:38-45.  </P >     <P   align="justify" >51 - Gallagher AM, Robson PJ, Livingstone MB, et al. Tracking of Energy and Nutrient    Intakes from Adolescence to Young Adulthood: The Experiences of the Young Hearts    Project, Northern Ireland. Public Health Nutr 2006;9:1027-34. </P >     <P   align="justify" >52 - Mikkila V, Rasanen L, Raitakari OT, Pietinen P, Viikari J. Consistent Dietary    Patterns Identified from Childhood to Adulthood: The Cardiovascular Risk in    Young Finns Study. Br J Nutr 2005;93:923-31. </P >     <P   align="justify" >53 - Addison CC, White MS, Jenkins BW, Young L. Combating the Epidemic of Obesity    and Cardiovascular Disease: Perspectives from School-Aged Children. Int J Environ    Res Public Health 2006;3:268-73. </P >     <P   align="justify" >54 - Barros H. Epidemiologia das Doen&ccedil;as Ateroscler&oacute;ticas. Rev    Port Cardiol 2000;19:7-74. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >55 - Ferreira I, Twinsk JW, Van Mechelen W, Kemper HC, Stehouwer CD. Development    of Fatness, Fitness, and Lifestyle from Adolescence to the Age of 36 Years:    Determinants of the Metabolic Syndrome in Young Adults: The Amsterdam Growth    and Health Longitudinal Study. Arch Intern Med 2005;165:42-8. </P >     <P   align="justify" >56 -Lagerros YT, Hsieh SF, Hsieh CC. Physical Activity in Adolescence and Young    Adulthood and Breast Cancer Risk: A Quantitative Review. Eur J Cancer Prev 2004;13:5-12.  </P >     <P   align="justify" >57 - Brosnahan J, Steffen LM, Lytle L, Patterson J, Boostrom A. The Relation    between Physical Activity and Mental Health among Hispanic and Non-Hispanic    White Adolescents. Arch Pediatr Adolesc Med 2004;158:818-23. </P >     <P   align="justify" >58 - Steptoe A, Butler N. Sports Participation and Emotional Wellbeing in Adolescents.    Lancet 1996;347:1789-92. </P >     <P   align="justify" >59 - Nelson MC, Gordon-Larsen P. Physical Activity and Sedentary Behavior Patterns    Are Associated with Selected Adolescent Health Risk Behaviors. Pediatrics 2006;117:    1281-90. </P >     <P   align="justify" >60 - Pate RR, Trost SG, Levin S, Dowda M. Sports Participation and Health-Related    Behaviors among Us Youth. Arch Pediatr & Adolesc Med 2000;154:904-11. </P >     <P   align="justify" >61 -Valois RF, Oeltmann JE, Waller J, Hussey JR. Relationship between Number of Sexual Intercourse Partners and Selected Health Risk Behaviors among Public High School Adolescents. J Adolesc Health 1999;25:328-35. </P >     <P   align="justify" >62 - Kulig K, Brener ND, McManus T. Sexual Activity and Substance Use among Adolescents    by Category of Physical Activity Plus Team Sports Participation. Arch Pediatr    Adolesc Med 2003;157:905-12. </P >     <P   align="justify" >63 - Aaron DJ, Dearwater SR, Aanderson R, Olsen T, Kriska AM, Laporte RE. Physical    Activity and the Initiation of High-Risk Health Behaviors in Adolescents. Med    Sci Sports Exerci 1995;27:1639-45. </P >     <P   align="justify" >64 -Tammelin T. A Review of Longitudinal Studies on Youth Predictors of Adulthood Physical Activity. Int J Adolesc Med Health 2005;17:3-12. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >65 - Reilly JJ, Jackson DM, Montgomery C, et al. Total Energy Expenditure and    Physical Activity in Young Scottish Children: Mixed Longitudinal Study. Lancet    2004;363:211-2. </P >     <P   align="justify" >66 - American Academy of Pediatrics: Children, Adolescents, and Television. Pediatrics    2001;107:423-6. </P >     <P   align="justify" >67 - Fonseca H, Gaspar de Matos M.Perception of Overweight and Obesity among    Portuguese Adolescents: An Overview of Associated Factors. Eur J Public Health    2005;15:323-8. </P >     <P   align="justify" >68 - Li S, Chen W, Srinivasan SR, et al. Childhood Cardiovascular Risk Factors    and Carotid Vascular Changes in Adulthood: The Bogalusa Heart Study. JAMA 2003;290:2271-6.  </P >     <P   align="justify" >69 - Zieske AW, Malcom GT, b JP. Natural History and Risk Factors of Atherosclerosis    in Children and Youth: The Pday Study. Pediatr Pathol Mol Med 2002;21:213-37.  </P >     <P   align="justify" >70 - Berenson GS. Childhood Risk Factors Predict Adult Risk Associated with Subclinical    Cardiovascular Disease. The Bogalusa Heart Study. Am J Cardiol 2002;90:3L-7L.  </P >     <P   align="justify" >71 - Freedman DS, Dietz WH, Tang R, et al. The Relation of Obesity Throughout    Life to Carotid Intima-Media Thickness in Adulthood: The Bogalusa Heart Study.    Int J Obes Relat Metab Disord 2004;28:159-66. </P >     <P   align="justify" >72 - Lobstein T, Rigby N, Leach R. UE Platform on Diet, Physical Activity and    Health. International Obesity Task Force Eu Platform Briefing Paper. [Cited    2005 Jul 12]. Available From: url <a href="http://europa.eu/" target="_blank">http://europa.eu.int/comm/health/ph_determinants/life_style/nutrition/documents/Iotf_en.pdf</a></P >     <P   align="justify" >73 - Banegas JR, Lopes-Garcia E, Gutierrez-Fisac JL, Guallar-Castillon P, Rodriguez-Artalejo    F. A Simple Estimate of Mortality Attributable to Excess Weight in the European    Union. Eur J Clin Nutr 2003;57:201-8. </P >     <P   align="justify" >74 - Marques-Vidal P, Dias CM. Trends in Overweight and Obesity in Portugal:    The National Health Surveys 1995-6 and 1998-9. Obes Res 2005;13:1141-5. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >75 - Nobre EL, Jorge Z, Macedo A, De Castro JJ. Trends of Weight, Height and    Obesity in Young Portuguese Males: 1995-1999. Eur J Epidemiol 2003;18:1165-6.  </P >     <P   align="justify" >76 - Santos AC, Barros H. Prevalence and Determinants of Obesity in an Urban    Sample of Portuguese Adults. Public Health 2003;117:430-7. </P >     <P   align="justify" >77 - Padez C, Fernandes T, Mour&atilde;o I, Moreira P, Rosado V. Prevalence of    Overweight and Obesity in 7-9-Year-Old Portuguese Children: Trends in Body Mass    Index from 1970-2002. Am J Hum Biol 2004;16:670-8. </P >     <P   align="justify" >78 - James PT, Leach R, Kalamara E, Shayeghi M. The Worldwide Obesity Epidemic.    Obes Res 2001;9:228S-33. </P >     <P   align="justify" >79 -Wang Y, Monteiro C, Popkin BM. Trends of Obesity and Underweight in Older Children and Adolescents in the United States, Brazil, China, and Russia. Am J Clin Nutr 2002;75:971-7. </P >     <P   align="justify" >80 - Dietz WH. Health Consequences of Obesity in Youth: Childhood Predictors    of Adult Disease. Pediatrics 1998;101:518-25. </P >     <P   align="justify" >81 - Srinivasan SR, Myers L, Berenson GS. Predictability of Childhood Adiposity    and Insulin for Developing Insulin Resistance Syndrome (Syndrome X) in Young    Adulthood: The Bogalusa Heart Study. Diabetes 2002;51:204-9. </P >     <P   align="justify" >82 - Engeland A, Bjorge T, Tverdal A, Sogaard AJ. Obesity in Adolescence and    Adulthood and the Risk of Adult Mortality. Epidemiology 2004;15:79-85. </P >     <P   align="justify" >83 - Regidor E, Banegas JR, Gutierrez-Fisac JL, Dominguez V, Rodriguez-Artalejo    F. Influence of Childhood Socioeconomic Circumstances, Height, and O-besity    on Pulse Pressure and Systolic and Diastolic Blood Pressure in Older People.    J Hum Hypertens 2006;20:73-82. </P >     <P   align="justify" >84 - Dietz WH. Periods of Risk in Childhood for the Development of Adult Obesity&mdash;What    Do We Need to Learn? J Nutr 1997;127:1884S-6S. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >85 - Freedman DS, Dietz WH, Srinivasan SR, Berenson GS. The Relation of Overweight    to Cardiovascular Risk Factors among Children and Adolescents: The Bogalusa    Heart Study. Pediatrics 1999;103:1175-82. </P >     <P   align="justify" >86 - Kohen-Avramoglu R, Theriault A, Adeli K. Emergence of the Metabolic Syndrome    in Childhood: An Epidemiological Overview and Mechanistic Link to Dyslipidemia.    Clin Biochem 2003;36:413-20. </P >     <P   align="justify" >87 - Dietz WH. Overweight in Childhood and Adolescence. N Engl J Med 2004;350:855-7.  </P >     <P   align="justify" >88 -Weiss R, Dziura J, Burgert TS, et al. Obesity and the Metabolic Syndrome in Children and Adolescents. N Engl J Med 2004;350:2362-74. </P >     <P   align="justify" >89 - Mustillo S, Worthman C, Erkanli A, Keeler G, Angold A, Costello EJ. Obesity    and Psychiatric Disorder: Developmental Trajectories. Pediatrics 2003; 111:851-9.  </P >     <P   align="justify" >90 - Levin S, Lowry R, Brown DR, Dietz WH. Physical Activity and Body Mass Index    among Us Adolescents: Youth Risk Behavior Survey, 1999. Arch Pediatr Adolesc    Med 2003; 157:816-20. </P >     <P   align="justify" >91 - Deforche B, Lefevre J, De Bourdeaudhuij I, Hills AP, Duquet W, Bouckaert    J. Physical Fitness and Physical Activity in Obese and Nonobese Flemish Youth.    Obes Res 2003;11:434-41. </P >     <P   align="justify" >92 - Whincup PH, Gilg JA, Donald AE, et al. Arterial Distensibility in Adolescents:    The Influence of Adiposity, the Metabolic Syndrome, and Classic Risk Factors.    Circulation 2005;112: 1789-97. </P >     <P   align="justify" >93 - Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a Standard Definition    for Child Overweight and Obesity Worldwide: International Survey. BMJ 2000;320:1240-3.  </P >     <P   align="justify" >94 - Kuczmarski RJ, Ogden CL, Guo SS, et al. 2000 Cdc Growth Charts for the United    States: Methods and Development. Vital Health Stat 11 2002;1-190. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >95 - Ramos E, Barros H. Family and School Determinants of Overweight in 13-Year-Old    Portuguese Adolescents. Acta Paediatr 2007;96:281-6. </P >     <P   align="justify" >96 - Daniels SR, Arnett DK, Eckel RH, et al. Overweight in Children and Adolescents:    Pathophysiology, Consequences, Prevention, and Treatment. Circulation 2005;111:    1999-2012. </P >     <P   align="justify" >97 - Koplan JP, Liverman CT, Kraak VI. Preventing Childhood Obesity: Health in    the Balance: Executive Summary. J Am Diet Assoc 2005;105:131-8. </P >     <P   align="justify" >98 - Williams CL, Hayman LL, Daniels SR, et al. Cardiovascular Health in Childhood:    A Statement for Health Professionals from the Committee on Atherosclerosis,    Hypertension, and Obesity in the Young (Ahoy) of the Council on Cardiovascular    Disease in the Young, American Heart Association. Circulation 2002;106:143-60.  </P >     <P   align="justify" >99 - Wolf-Maierk, Cooper RS, Banegas JR, et al. Hypertension Prevalence and Blood    Pressure Levels in 6 European Countries, Canada, and the United States. JAMA    2003;289: 2363-9. </P >     <P   align="justify" >100 - Lawlor DA, Smith GD. Early Life Determinants of Adult Blood Pressure. Curr    Opin Nephrol Hypertens 2005; 14:259-64. </P >     <P   align="justify" >101 -Yong LC, Kuller LH, Rutan G, Bunker C. Longitudinal Study of Blood Pressure: Changes and Determinants from Adolescence to Middle Age. The Dormont High School Follow-up Study, 1957-1963 to 1989-1990. Am J Epidemiol 1993;138:973-83. </P >     <P   align="justify" >102 - Bao W, Threefoot SA, Srinivasan SR, Berenson GS. Essential Hypertension    Predicted by Tracking of Elevated Blood Pressure from Childhood to Adulthood:    The Bogalusa Heart Study. Am J Hypertens 1995;8:657-65. </P >     <P   align="justify" >103 - Miura K, Daviglus ML, Dyer AR, et al. Relationship of Blood Pressure to    25-Year Mortality Due to Coronary Heart Disease, Cardiovascular Diseases, and    All Causes in Young Adult Men: The Chicago Heart Association Detection Project    in Industry. Arch Intern Med 2001;161:1501-8. </P >     <P   align="justify" >104 - Macedo ME, Lima MJ, Silva AO, Alcantara P, Ramalhinho V, Carmona J. Prevalence,    Awareness, Treatment and Control of Hypertension in Portugal: The Pap Study.    J Hypertens 2005;23:1661-6. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >105 - Santos AC, Lopes C, Barros H. Prevalence of Metabolic Syndrome in the City    of Porto. Rev Port Cardiol 2004;23:45-52. </P >     <P   align="justify" >106 - Ramos E, Barros H. Prevalence of Hypertension in 13-Year-Old Adolescents    in Porto, Portugal. Rev Port Cardiol 2005;24:1075-87. </P >     <P   align="justify" >107 - Duarte JA, Guerra SC, Ribeiro JC, Mota RC. Blood Pressure in Pediatric    Years (8-13 Years Old) in the Oporto Region. Rev Port Cardiol 2000;19:809-20.  </P >     <P   align="justify" >108 - Macedo ME, Lopes L, Pereira A, De Freitas AF. Blood Pressure Normal Values    in Children and Adolescents According to Age and Height. Rev Port Cardiol 1997;16:    679-82, 63. </P >     <P   align="justify" >109 - Sokol SI, Kapoor JR, Foody JM. Blood Pressure Reduction in the Primary    and Secondary Prevention of Stroke. Curr Vasc Pharmacol 2006;4:155-60. </P >     <P   align="justify" >110 -Turnbull F, Neal B, Algert C, et al. Effects of Different Blood Pressure-Lowering Regimens on Major Cardiovascular Events in Individuals with and without Diabetes Mellitus: Results of Prospectively Designed Overviews of Randomized Trials. Arch Intern Med 2005;165:1410-9. </P >     <P   align="justify" >111 - Reaven GM. Banting Lecture 1988. Role of Insulin Resistance in Human Disease.    Diabetes 1988;37:1595-607. </P >     <P   align="justify" >112 - Lakka HM LD, Laaka TA, Niskanen LK, et al. The Metabolic Syndrome and Total    and Cardiovascular Disease Mortality in Middle-Aged Men. JAMA 2002;288:2709-16.  </P >     <P   align="justify" >113 - Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol    in Adults. Executive Summary of the Third Report of the National Cholesterol    Education Program (Ncep) Expert Panel on Detection, Evaluation, and Treatment    of High Blood Cholesterol in Adults (Adult Treatment Panel Iii). JAMA 2001;285:2482-97.  </P >     <P   align="justify" >114 - Andersen LB, Wedderkopp N, Hansen HS, Cooper AR, Froberg K. Biological    Cardiovascular Risk Factors Cluster in Danish Children and Adolescents: The    European Youth Heart Study. Prev Med 2003;37:363-7. </P >     ]]></body>
<body><![CDATA[<P   align="justify" >115 - Steinberg J, Daniels SR. Obesity, Insulin Resistance, Diabetes, and Cardiovascular    Risk in Children: An American Heart Association Scientific Statement from the    Atherosclerosis, Hypertension, and Obesity in the Young Committee (Council on    Cardiovascular Disease in the Young) and the Diabetes Committee (Council on    Nutrition, Physical Activity, and Metabolism). Circulation 2003;107:1448-53.  </P >     <P   align="justify" >116 - Cruz ML, Weigensberg MJ, Huang TT, Ball G, Shaibi GQ, Goran MI. The Metabolic    Syndrome in Overweight Hispanic Youth and the Role of Insulin Sensitivity. J    Clin Endocrinol Metab 2004;89:108-13. </P >     <P   align="justify" >117 - Chen W, Srinivasan SR, Elkasabany A, Berenson GS. Cardiovascular Risk Factors    Clustering Features of Insulin Resistance Syndrome (Syndrome X) in a Biracial    (Black-White) Population of Children, Adolescents, and Young Adults: The Bogalusa    Heart Study. Am J Epidemiol 1999;150:667-74. </P >     <P   align="justify" >118 - Clausen JO, Ibsen H, Ibsen KK, Borch-Johnsen K. Association of Body Mass    Index, Blood Pressure and Serum Levels of Triglycerides and High-Density Lipoprotein    Cholesterol in Childhood with the Insulin Sensitivity Index in Young Adulthood:    A 13-Year Follow-Up. J Cardiovasc Risk 1996;3:427-33. </P >     <P   >119 - Vos LE, Oren A, Uiterwaal C, Gorissen WH, Grobbee DE,   Bots ML. Adolescent Blood Pressure and Blood Pressure   Tracking into Young Adulthood Are Related to Subclinical   Atherosclerosis: The Atherosclerosis Risk in Young Adults   (Arya) Study. Am J Hypertens 2003;16:549-55.</P >     <P   >120 - Goodman E, Daniels SR, Morrison JA, Huang B, Dolan   LM. Contrasting Prevalence of and Demographic Disparities   in the World Health Organization and National Cholesterol   Education Program Adult Treatment Panel Iii   Definitions of Metabolic Syndrome among Adolescents. J   Pediatr 2004;145:445-51.</P >     <P   >121 - Rodriguez-Moran M, Salazar-Vazquez B, Violante R,   Guerrero-Romero F. Metabolic Syndrome among Children   and Adolescents Aged 10-18 Years. Diabetes Care   2004;27:2516-7.</P >     <P   >122 - Chen W, Bao W, Begum S, Elkasabany A, Srinivasan SR,   Berenson GS. Age-Related Patterns of the Clustering of   Cardiovascular Risk Variables of Syndrome X from Childhood   to Young Adulthood in a Population Made up of   Black and White Subjects: The Bogalusa Heart Study.   Diabetes 2000;49:1042-8.</P >     <P   >123 - Duncan GE, Li SM, Zhou XH. Prevalence and Trends of   a Metabolic Syndrome Phenotype among U.S. Adolescents,   1999-2000. Diabetes Care 2004;27:2438-43.</P >     <P   >124 - De Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ,   Newburguer JW, Rifai N. Prevalence of the Metabolic   Syndrome in American Adolescents: Findings from the   Third National Health and Nutrition Examination Survey.   Circulation 2004;110:2494-7.</P >     ]]></body>
<body><![CDATA[<P   >125 - Ramos E. Health Determinants in Porto Adolescents. The   Epiteen Cohort. Porto: University of Porto; 2006.</P >     <P   >126 - Holland P, Berney L, Blane D, Smith GD, Gunnell DJ,   Momtgomery SM. Life Course Accumulation of Disadvantage:   Childhood Health and Hazard Exposure During   Adulthood. Soc Sci Med 2000;50:1285-95.</P >     <P   >127 - Smith GD, Hart C. Life-Course Socioeconomic and Behavioral   Influences on Cardiovascular Disease Mortality:   The Collaborative Study. Am J Public Health 2002;92:1295-8.</P >     <P   >128 - Smith GD, Hart C, Blane D, Hole D. Adverse Socioeconomic   Conditions in Childhood and Cause Specific Adult   Mortality: Prospective Observational Study. BMJ   1998;316:1631-5.</P >     <P   >129 - Bush A. Asthma Research: The Real Action Is in Children.   Paediatr Respir Rev 2005;6:101-10.</P >     <P   >130 - Baik I, Devito WJ, Ballen K, et al. Association of Fetal   Hormone Levels with Stem Cell Potential: Evidence for   Early Life Roots of Human Cancer. Cancer Res 2005;65:   358-63.</P >     <P   >131 - Forman MR, Cantwell MM, Ronckers C, Zhang Y. Through   the Looking Glass at Early-Life Exposures and Breast   Cancer Risk. Cancer Invest 2005;23:609-24.</P >     <P   >&nbsp;</P >     <P   ><b>Correspond&ecirc;ncia</b>: </P >     <P   >Dr&ordf; Elisabete Ramos Servi&ccedil;o de Higiene e Epidemiologia </P >     ]]></body>
<body><![CDATA[<P   >Faculdade de Medicina da Universidade do Porto </P >     <P   >Alameda Prof. Hern&acirc;ni Monteiro 4200-319 Porto</P >     <P>e-mail: <a href="mailto:eliramos@med.up.pt">eliramos@med.up.pt</a> </P>     <P>&nbsp;</P>      ]]></body><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Steinberg]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
</person-group>
<article-title xml:lang="en"><![CDATA[Cognitive and Affective Development in Adolescence]]></article-title>
<source><![CDATA[Trends Cogn Sci]]></source>
<year>2005</year>
<volume>9</volume>
<page-range>69-74</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
