<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0871-9721</journal-id>
<journal-title><![CDATA[Revista Portuguesa de Imunoalergologia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Port Imunoalergologia]]></abbrev-journal-title>
<issn>0871-9721</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Alergologia e Imunologia Clínica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0871-97212022000400263</article-id>
<article-id pub-id-type="doi">10.32932/rpia.2022.12.092</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Anafilaxia no idoso: Particularidades na abordagem diagnóstica e terapêutica]]></article-title>
<article-title xml:lang="en"><![CDATA[Anaphylaxis in the elderly: Diagnostic and therapeutic management particularities]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Brosseron]]></surname>
<given-names><![CDATA[Lise]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ferreira]]></surname>
<given-names><![CDATA[Ana Reis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Hospitalar Vila Nova de Gaia/Espinho, EPE Serviço de Imunoalergologia ]]></institution>
<addr-line><![CDATA[Vila Nova de Gaia ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>12</month>
<year>2022</year>
</pub-date>
<volume>30</volume>
<numero>4</numero>
<fpage>263</fpage>
<lpage>276</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S0871-97212022000400263&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S0871-97212022000400263&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S0871-97212022000400263&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO Com o aumento global da esperança média de vida e consequente prevalência crescente de patologias relacionadas com o envelhecimento, as doenças do foro alérgico não são exceção, sendo cada vez mais frequentes na prática clínica diária. A anafilaxia, enquanto reação de hipersensibilidade grave e potencialmente fatal, encontra&#8209;se associada a uma maior morbimortalidade nesta faixa etária, apresentando particularidades próprias que merecem ser destacadas, não só ao nível do diagnóstico, como do seu tratamento. A presença de múltiplas comorbilidades e consequente polimedicação, frequentemente com fármacos anti&#8209;hipertensores que podem não só condicionar reações anafiláticas, como também dificultar o tratamento destas, juntamente com o predomínio de sintomas cardiovasculares e outros fatores inerentes ao envelhecimento, conferem maior vulnerabilidade a esta população. Assim, torna&#8209;se pertinente identificar e sensibilizar os profissionais de saúde para a existência de características particulares da anafilaxia no idoso, de modo a permitir uma intervenção mais direcionada e uma melhoria no prognóstico destes doentes.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT The global increase in life expectancy is associated to the rising prevalence of pathologies typically related to aging, with allergic diseases being growingly described. Anaphylaxis, a severe and potentially fatal hypersensitivity reaction, is associated with higher morbidity and mortality in this age group, presenting particularities that deserve to be highlighted, not only regarding its diagnosis but also its treatment. The existence of multiple comorbidities resulting in polymedication, namely with antihypertensive drugs that may not only condition anaphylactic reactions but also hinder their treatment, together with the predominance of cardiovascular symptoms and other age associated factors, confer greater vulnerability to this population. It is therefore pertinent to identify and raise awareness of the existence of particularities of anaphylaxis in the elderly, allowing a more directed intervention and improvement in prognosis.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Anafilaxia]]></kwd>
<kwd lng="pt"><![CDATA[comorbilidades]]></kwd>
<kwd lng="pt"><![CDATA[envelhecimento]]></kwd>
<kwd lng="pt"><![CDATA[idoso]]></kwd>
<kwd lng="en"><![CDATA[Aging]]></kwd>
<kwd lng="en"><![CDATA[anaphylaxis]]></kwd>
<kwd lng="en"><![CDATA[comorbidities]]></kwd>
<kwd lng="en"><![CDATA[elderly]]></kwd>
</kwd-group>
</article-meta>
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