<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0872-1904</journal-id>
<journal-title><![CDATA[Portugaliae Electrochimica Acta]]></journal-title>
<abbrev-journal-title><![CDATA[Port. Electrochim. Acta]]></abbrev-journal-title>
<issn>0872-1904</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Electroquímica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0872-19042006000200004</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[A brief overview about the proteins and the processes responsible for the formation of the nativ-folded thioproteins in the pro-and eukaryotic cells]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kruusma]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Benham]]></surname>
<given-names><![CDATA[A.M.]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Williams]]></surname>
<given-names><![CDATA[J.A.G.]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kataky]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,University of Tartu Institute of Physical Chemistry ]]></institution>
<addr-line><![CDATA[Tartu ]]></addr-line>
<country>Estonia</country>
</aff>
<aff id="A02">
<institution><![CDATA[,University of Durham The Centre for Bioactive Chemistry ]]></institution>
<addr-line><![CDATA[Durham ]]></addr-line>
<country>U.K</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2006</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2006</year>
</pub-date>
<volume>24</volume>
<numero>2</numero>
<fpage>207</fpage>
<lpage>228</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S0872-19042006000200004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S0872-19042006000200004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S0872-19042006000200004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[This review was erected to describe briefly proteins and processes responsible for the formation of the nativ-folded thioproteins in the pro- and eukaryotic cells. This issue has a significant importance due to many dieases and misfunctions caused by misfolded enzymes having low or inactive structure. This review contains also a short list of electrochemical methods for the detection and the quantification of the most important thioproteins.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[thiol proteins]]></kwd>
<kwd lng="en"><![CDATA[electrochemistry]]></kwd>
<kwd lng="en"><![CDATA[protein disulfide isomerase]]></kwd>
<kwd lng="en"><![CDATA[eukaryotic cells]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <p align="center"><b>A brief overview about the proteins and the processes responsible    for the formation of the nativ-folded thioproteins in the pro-and eukaryotic    cells </b></p>     <p align="center"><b>J. Kruusma,</b><i ><sup>a</sup></i><b > A.M. Benham,</b><i><sup>b</sup></i><b >    J.A.G. Williams,</b><i><sup>b</sup></i><b > R. Kataky </b><i><sup>b,</sup></i><b><a href="#1">*</a><a name="top1"></a></b></p>     <p align="center">&nbsp;</p>     <p align="center"><i ><sup>a</sup></i><i> Institute of Physical Chemistry, </i><i>University</i><i>    of </i><i >Tartu</i><i>, Jakobi 2,    </i><i >sTartu</i><i>, 51014, </i><i>Estonia</i></p>     <p align="center"><i><sup>b</sup></i><i >The Centre for Bioactive Chemistry, </i><i >University</i><i>    of </i><i >Durham</i><i>, </i><i>South    Road</i><i>,  </i><i>Durham</i><i >, </i><i>DH1    4HT</i><i>, </i><i >U.K.</i></p>     <p align="center"></p>      <p>&nbsp;</p>      <p><b>Abstract</b></p>      <p align="justify">This review was erected to describe briefly proteins and processes    responsible for the formation of the nativ-folded thioproteins in the pro- and    eukaryotic cells. This issue has a significant importance due to many dieases    and misfunctions caused by misfolded enzymes having low or inactive structure.</p>     <p align="justify">This review contains also a short list of electrochemical methods    for the detection and the quantification of the most important thioproteins.</p>     ]]></body>
<body><![CDATA[<p align="justify"><b><i >Keywords: </i></b>thiol proteins, electrochemistry,    protein disulfide isomerase, eukaryotic cells.</p>      <p>&nbsp;</p>      <p>Texto disponível em PDF</p>      <p>Full text only in PDF format</p>      <p>&nbsp;</p>      <p><b >References</b></p>      <p>1. <a href="http://www.mathcell.ru/show_topic_en.php?file=end_sh" target="_blank">http://www.mathcell.ru/show_topic_en.php?file=end_sh</a></p>       <!-- ref --><p>2. J. Rutishauser and M. Spiess, <i>Swiss Med WKLY</i>  132 (2002) 211.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000020&pid=S0872-1904200600020000400001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><p>3. C. Hwang, A.J. Sinskey, H.F. Lodish, <i >Science</i> 257 (1992) 1496.</p>        <p>4. J. Qin, Y. Yang, A. Velyvis and A. Gronenborn, <i >Antioxidants &amp; Redox Signaling</i> 2 (2000) 827.</p>       ]]></body>
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<body><![CDATA[<p>&nbsp;</p>                    <p><a href="#top1">*</a><a name="1"></a>Corresponding author. E-mail address:    <a href="mailto:Ritu.kataky@durham.ac.uk">Ritu.kataky@durham.ac.uk</a>.</p>           ]]></body><back>
<ref-list>
<ref id="B1">
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<name>
<surname><![CDATA[Rutishauser]]></surname>
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<surname><![CDATA[Spiess]]></surname>
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<source><![CDATA[Swiss Med WKLY]]></source>
<year>2002</year>
<numero>132</numero>
<issue>132</issue>
<page-range>211</page-range></nlm-citation>
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