<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0872-8178</journal-id>
<journal-title><![CDATA[Jornal Português de Gastrenterologia ]]></journal-title>
<abbrev-journal-title><![CDATA[J Port Gastrenterol.]]></abbrev-journal-title>
<issn>0872-8178</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Gastrenterologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0872-81782006000500005</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Tumor do estroma gástrico em doente jovem]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mendes]]></surname>
<given-names><![CDATA[S.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Romão]]></surname>
<given-names><![CDATA[Z.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ferreira]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Meruje]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Magalhães]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
<xref ref-type="aff" rid="A03"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Campos]]></surname>
<given-names><![CDATA[M. J.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Centro Hospitalar de Coimbra Serviço de Gastrenterologia ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A02">
<institution><![CDATA[,Centro Hospitalar de Coimbra Serviço de Anatomia Patológica ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A03">
<institution><![CDATA[,Centro Hospitalar de Coimbra Serviço de Cirurgia 2 ]]></institution>
<addr-line><![CDATA[Coimbra ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2006</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2006</year>
</pub-date>
<volume>13</volume>
<numero>5</numero>
<fpage>233</fpage>
<lpage>236</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S0872-81782006000500005&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S0872-81782006000500005&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S0872-81782006000500005&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Os autores apresentam o caso de uma doente internada por episódio de hemorragia digestiva alta com origem num tumor do estroma gastrointestinal (GIST). Salientam o facto de se tratar de uma jovem e a importância da eco-endoscopia no diagnóstico e caracterização deste tipo de tumores. A propósito do caso clínico, fazem uma breve revisão do tema.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[The authors present a clinical case of a patient hospitalized for acute upper gastrointestinal bleeding originating from a gastrointestinal stromal tumour (GIST). They highlight the young age of this female patient and the relevance of endoscopic ultrasound both in diagnosis and in characterization of these sorts of tumours. This clinical case serves as a springboard for a short review of the topic.]]></p></abstract>
</article-meta>
</front><body><![CDATA[ <p><b>Tumor do estroma g&aacute;strico em doente jovem</b></p>         <p>S. Mendes<a href="#4">*</a><a name="top4"></a><sup><a href="#1">1</a><a name="top1"></a></sup>,    Z. Rom&atilde;o<sup><a href="#1">1</a></sup><a name="top1"></a>, M. Ferreira<sup><a href="#1">1</a></sup><a name="top1"></a>,    M. Meruje<sup><a href="#2">2</a><a name="top2"></a></sup>, C. Magalh&atilde;es<sup><a href="#3">3</a><a name="top3"></a></sup>,    M. J. Campos<sup><a href="#1">1</a><a name="top1"></a></sup></p>       <p>&nbsp;</p>      <p><b><i>Resumo</i></b></p>      <p align="justify">Os autores apresentam o caso de uma doente internada por episódio    de hemorragia digestiva alta com origem num tumor do estroma gastrointestinal    (GIST).</p>     <p align="justify">Salientam o facto de se tratar de uma jovem e a importância    da eco-endoscopia no diagnóstico e caracterização deste tipo de tumores.</p>     <p align="justify">A propósito do caso clínico, fazem uma breve revisão do tema.</p>     <p align="justify">&nbsp;</p>        <p><b><i>Summary</i></b></p>        <p align="justify">The authors present a clinical case of a patient hospitalized    for acute upper gastrointestinal bleeding originating from a gastrointestinal    stromal tumour (GIST).</p>     ]]></body>
<body><![CDATA[<p align="justify">They highlight the young age of this female patient and the    relevance of endoscopic ultrasound both in diagnosis and in characterization    of these sorts of tumours.</p>     <p align="justify">This clinical case serves as a springboard for a short review    of the topic.</p>       <p>&nbsp;</p>      <p>Texto Completo disponível apenas em PDF</p>      <p>Full text only available in PDF format</p>      <p>&nbsp;</p>       <p><b>Bibliografia</b></p>      <!-- ref --><p>1. Davila RE, Faigel DO. GI stromal tumors. Gastrointest Endosc 2003; 58: 80-88.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000020&pid=S0872-8178200600050000500001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><p>2. Nowain A, Bhakta H, Pais S, Kanel G, Verma S. Gastrointestinal stromal tumors: Clinical profile, pathogenesis, treatment strategies and prognosis. J Gastroenterol Hepatol. 2005; 20: 818-24.</p>      <p >3. Dematteo RP, Heinrich MC, El-Rifai WM, et al. Clinical Management of Gastrointestinal Stromal Tumors: Before and After STI-571. Human Pathology 2002; 33: 466-477.</p>      ]]></body>
<body><![CDATA[<p>4. Fletcher C, Berman JJ, Corless C, et al. Diagnosis of Gastrointestinal Stromal Tumors: A Consensus Approach. Human Pathology 2002; 33: 459-465.</p>      <p>5. Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 1998; 279: 577-80.</p>      <p>6. Kitamura Y, Hirota S, Nishida T. Gastrointestinal stromal tumors (GIST): a model for molecule-based diagnosis and treatment of solid tumors. Cancer Sci. 2003; 94: 315-20.</p>      <p>7. Moreira MJ, Amaro P, Romãozinho JM, et al. Tumores de Estroma Gstrointestinal como Causa de Hemorragia de Causa Obscura &#8211; A propósito de um Caso Clínico. Revista Portuguesa de Coloproctologia 2004, 1 (3): 32-37.</p>      <p>8. Polkowski  M. Endoscopic Ultrasound and Ultrasound-Guided Fine-Needle Biopsy for the Diagnosis of Malignant Submucosal Tumors. Endoscopy 2005; 37: 613-694.</p>      <p>9. Blay JY, Bonvalot S, Casali P, et al. Consensus meeting for management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO. Annals of Oncology 2005; 16: 566-578.</p>      <p>10. Nickl NJ. Gastrointestinal stromal tumors: new progress, new questions. Curr Opin Gastroenterol. 2004; 20: 427-516.</p>         <p>11. Duffaud F, Blay Jean-Yves. Gastrointestinal Stromal Tumors: Biology and    Treatment. Oncology 2003; 65: 187-197.</p>     <p>&nbsp;</p>     <p><a href="#top4">*</a><a name="4"></a>Correspondência:</p>     ]]></body>
<body><![CDATA[<p>Sofia Mendes</p>         <p>Serviço      de Gastrenterologia</p>       <p>Centro      Hospitalar de Coimbra &#8211; Hospital Geral</p>        <p>Quinta dos Vales, S. Martinho do Bispo</p>       <p>3046-853      Coimbra.</p>       <p>Tel.: 239800131</p>        <p><i>e-mail: </i><a href="mailto:msofiamendes@iol.pt">msofiamendes@iol.pt</a></p>       <p >&nbsp;</p>        <p >(<a href="#top1">1</a><a name="1"></a>) Serviço de Gastrenterologia.</p>        <p>(<a href="#top2">2</a><a name="2"></a>) Serviço de Anatomia Patológica.</p>        ]]></body>
<body><![CDATA[<p>(<a href="#top3">3</a><a name="3"></a>) Serviço de Cirurgia 2.</p>       <p>Centro Hospitalar de Coimbra, Coimbra, Portugal.</p>       <p>&nbsp;</p>         <p align="right">Recebido para publicação: 28/11/2005</p>        <p align="right">Aceite para publicação: 31/05/2006</p>         ]]></body><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Davila]]></surname>
<given-names><![CDATA[RE]]></given-names>
</name>
<name>
<surname><![CDATA[Faigel]]></surname>
<given-names><![CDATA[DO]]></given-names>
</name>
</person-group>
<article-title xml:lang="en"><![CDATA[GI stromal tumors]]></article-title>
<source><![CDATA[Gastrointest Endosc]]></source>
<year>2003</year>
<volume>58:</volume>
<page-range>80-88</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
