<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0873-2159</journal-id>
<journal-title><![CDATA[Revista Portuguesa de Pneumologia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Port Pneumol]]></abbrev-journal-title>
<issn>0873-2159</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Pneumologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0873-21592008000100008</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Os abcessos pulmonares em revisão]]></article-title>
<article-title xml:lang="en"><![CDATA[Pulmonary abcess, a revision]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gonçalves]]></surname>
<given-names><![CDATA[Ana Moura]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Falcão]]></surname>
<given-names><![CDATA[Luiz Menezes]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ravara]]></surname>
<given-names><![CDATA[Luciano]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Universidade de Lisboa Faculdade de Medicina de Lisboa Hospital de Santa Maria]]></institution>
<addr-line><![CDATA[Lisboa ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>02</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>02</month>
<year>2008</year>
</pub-date>
<volume>14</volume>
<numero>1</numero>
<fpage>141</fpage>
<lpage>149</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S0873-21592008000100008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S0873-21592008000100008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S0873-21592008000100008&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Os abcessos pulmonares são cavidades que surgem no parênquima pulmonar, apresentando maior ou menor quantidade de tecido necrosado no seu interior. Surgem em indivíduos predispostos, como sejam os doentes com doença pulmonar crónica ou obstrução secundária a neoplasia e os doentes com maior risco de aspiração, estando incluidos os doentes com alteração do estado neurológico, os utilizadores de drogas endovenosas, os doentes com alcoolismo, patologia da faringe e esofágica, doença neuromuscular, entre outras. É feita a revisão dos principais agentes causais, da metodologia diagnóstica, da abordagem terapêutica na actualidade e do prognóstico destas situações. Os abcessos pulmonares, para além de relativamente pouco frequentes, são difíceis de caracterizar, sendo a resistência aos antibióticos um problema a ter presente, na sua abordagem terapêutica.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Lung abscesses are cavitating lesions containing necrotic debris caused by microbial infection. Patients with chronic lung disease, bronchial obstruction secondary to cancer, a history of aspiration or risk of aspiration caused by alcoholism, altered mental status, structural or physiologic alterations of the pharynx and esophagus, neuromuscular disorders, anesthesia, are among others at higher risk of developing lung abcess. The main bacteriological characteristics, the diagnosis, therapy and prognosis are considered. The problem of antimicrobial resistance is also referred.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Abcesso pulmonar]]></kwd>
<kwd lng="pt"><![CDATA[pneumonia de aspiração]]></kwd>
<kwd lng="pt"><![CDATA[resistência antimicrobiana]]></kwd>
<kwd lng="pt"><![CDATA[anaeróbios]]></kwd>
<kwd lng="en"><![CDATA[Lung abscesses]]></kwd>
<kwd lng="en"><![CDATA[aspiration pneumonia]]></kwd>
<kwd lng="en"><![CDATA[antimicrobial resistance]]></kwd>
<kwd lng="en"><![CDATA[anaerobes]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <p><b>Os abcessos pulmonares em revisão  </b></p>      <p><b> Pulmonary abcess, a revision </b></p>     <p>&nbsp;</p>          <p><b> Ana Moura Gonçalves <a href="#1">1</a><a name="top1"></a></b></p>      <p><b> Luiz Menezes Falcão <a href="#2">2</a> <a name="top2"></a></b></p>      <p><b> Luciano Ravara <a href="#3">3</a></b> <a name="top3"></a></p>     <p>&nbsp;</p>     <p>&nbsp;</p>          <p><b> Resumo  </b></p>      <p> Os abcessos pulmonares são cavidades que surgem no parênquima pulmonar, apresentando    maior ou menor quantidade de tecido necrosado no seu interior. Surgem em indivíduos    predispostos, como sejam os doentes com doença pulmonar crónica ou obstrução    secundária a neoplasia e os doentes com maior risco de aspiração, estando incluidos    os doentes com alteração do estado neurológico, os utilizadores de drogas endovenosas,    os doentes com alcoolismo, patologia da faringe e esofágica, doença neuromuscular,    entre outras. É feita a revisão dos principais agentes causais, da metodologia    diagnóstica, da abordagem terapêutica na actualidade e do prognóstico destas    situações. </p>      ]]></body>
<body><![CDATA[<p> Os abcessos pulmonares, para além de relativamente pouco frequentes, são difíceis de caracterizar, sendo a resistência aos antibióticos um problema a ter presente, na sua abordagem terapêutica.  </p>         <p><b> Palavras-chave: </b> Abcesso pulmonar, pneumonia de aspiração, resistência    antimicrobiana, anaeróbios.</p>     <p>&nbsp;</p>     <p>&nbsp;</p>      <p><b> Abstract  </b></p>      <p> Lung abscesses are cavitating lesions containing necrotic debris caused by microbial infection. Patients with chronic lung disease, bronchial obstruction secondary to cancer, a history of aspiration or risk of aspiration caused by alcoholism, altered mental status, structural or physiologic alterations of the pharynx and esophagus, neuromuscular disorders, anesthesia, are among others at higher risk of developing lung abcess.  </p>      <p> The main bacteriological characteristics, the diagnosis, therapy and prognosis are considered. The problem of antimicrobial resistance is also referred.  </p>                  <p><b> Key-words: </b> Lung abscesses, aspiration pneumonia, antimicrobial resistance, anaerobes   </p>         <p>&nbsp;</p>     <p>&nbsp;</p>     ]]></body>
<body><![CDATA[<p>Texto completo dispon&iacute;vel apenas em PDF.</p>       <p>Full text only available in PDF format.</p>             <p>&nbsp;</p>     <p>&nbsp;</p>     <p><b>Bibliografia </b></p>      <p>&nbsp; </p>     <!-- ref --><p>1. Tan QT, Seilheimer DK., Kaplan SL. Pediatric lung abscess: clinical management    and outcome. Pediatric Infect Dis J 1995; 14:51-5. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000029&pid=S0873-2159200800010000800001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><p> 2. Bartlett JG. Anaerobic bacterial pleuropulmonary infections. Semin Respir Med 1992; 13:159-64.  </p>      <p> 3. Smith DT. Experimental aspiratory abscess. Arch Surg 1927; 14:231-9.  </p>      <p> 4. Smith DT. Fuso-spirochetal disease of the lungs. Tubercle 1928; 9:420.  </p>      ]]></body>
<body><![CDATA[<p> 5. Weiss W, Cherniack NS. Acute nonspecific lung abscess: a controlled study comparing orally and parenterally administered penicillin G. Chest 1974; 66:348-51.  </p>      <p> 6. Bartlett JG: HIV infection and surgeons. Curr Probl Surg 1992; 197-280.  </p>      <p> 7. Pohlson EC, McNamara JJ, Char C, <i>et al</i>: Lung abscess: a changing pattern of the disease. Am J Surg 1985 Jul; 150:97-101.  </p>      <p> 8. Hirshberg B, Sklair-Levi M, Nir-Paz R:Factors predicting mortality of patients with lung abscess. Chest 1999 Mar; 115:746-50.  </p>      <p> 9. Bartlett, JG. Lung abscess and the necrotizing pneumonia. <i>In</i>: Gorbach SL, Bartlett JG, Blacklow NR (Eds.). Infectious Diseases. WB Saunders, Philadelphia 1992.  </p>      <p> 10. Davis B, Systrom DM. Lung abscess: pathogenesis, diagnosis and treatment.  Curr Clin Topics Infect Dis 1998; 18:252-73.  </p>      <p> 11. Wang J-L, Chen K-Y, Fang C-T <i>et al</i>.  Changing Bacteriology of Adult Community-Acquired Lung Abscess in Taiwan: <i>Klebsiella pneumoniae </i>versus Anaerobes. CID 2005; 40:915-22.  </p>      <p> 12. Yoneyama T, Yoshida M, Matsui T, Sasaki H. Oral care and pneumonia. Lancet 1999; 354:515.  </p>      <p> 13. Chung G, Goetz MB. Anaerobic infections of the lung. Curr Infect Dis Rep 2000; 2:238-44.  </p>      <p> 14. Marik PE. Aspiration pneumonitis and aspiration pneumonia. N Engl J Med 2001; 344(9):665-71.  </p>      ]]></body>
<body><![CDATA[<p> 15. Torres A, Serra- Batlles J, Ferrer A, <i>et al</i>. Severe community-acquired pneumonia: epidemiology and prognostic factors. Am Ver Respir Dis 1991; 144:312-8.  </p>      <p> 16. Moine P, Vercken JP, Chevret S, Chastang C, Gajdos P. Severe Community-acquired pneumonia: etiology, epidemiology, and prognosis factors. Chest 1994; 105:1487-95.  </p>      <p> 17. Olsson GL, Hallen B, Hambraeus-Jonzon K. Aspiration during anaesthesia: a computer-aided study of 185.358 anaesthesics. Acta Anaesthesiol Scand 1986; 30:84-92.  </p>      <p> 18. Holas MA, DePippo KL, Reding MJ. Aspiration and relative risk of medical complications following stroke. Arch Neurol 1994; 51:1051-3.  </p>      <p> 19. Mann G, Hankey GJ, Cameron D. Swallowing function after stroke: prognosis and prognostic factors at 6 months. Stroke 1999; 30:744 -8.  </p>      <p> 20. Roy TM, Ossorio MA, Cipolla LM, Fields CL, Snider HL, Anderson WH. Pulmonary complications after tricyclic antidepressant overdose. Chest 1989; 96:852-6.  </p>      <p> 21. Aldrich T, Morrison J, Cesário T. Aspiration after overdosage of sedative or hypnotic drugs. South Med J 1980; 73:456-8.  </p>      <p> 22. Warner MA, Warner ME, Weber JG. Clinical significance of pulmonary aspiration during the perioperative period. Anesthesiology 1993; 78:56-62.  </p>      <p> 23. Bartlett JG, Gorbach SL, Tally FP, Finegold SM. Bacteriology and treatment of primary lung abscess. AM Rev Respir Dis 1974; 109:510.  </p>      <p> 24. Fisher AM, Trever RW, Curtin JA <i>et al</i>. Staphylococcal pneumonia; a review of 21 cases in adults.  N Engl J Med 1958; 258:919-28.  </p>      ]]></body>
<body><![CDATA[<p> 25. Bartlett JG. The role of Anaerobic Bacteria in Lung Abscess. CID 2005; 40:923-5.  </p>      <p> 26. Bartlett JG. Anaerobic bacterial infections of the lung. Chest 1987; 91:901-9.  </p>      <p> 27. Bartlett JG. Anaerobic bacterial infections of the lung and pleural space. Clin Infect Dis 1993;16: S248-55.  </p>      <p> 28. Clinical conferences at the Johns Hopkins Hospital: lung abscess. Johns    Hopkins Med J 1982; 150:141-7.</p>     <p> 29. Pfitzner J, Peacock MJ, Tsirgiotis E, Walkley H. Lobectomy for cavitating    lung abscess with haemoptysis: Strategy for protecting the contralateral lung    and also the non-involved lobe of the ipsilateral lung. Br J Anaesth 2000; 85,    n.º 5:791-4. </p>      <p> 30. Stark DD, Federle MP, Goodman PC <i>et al</i>. Differentiating lung abscess and empyema: radiography and computed tomography. Am J Roentgenol 1983; 141:163-7.  </p>      <p> 31. Irwin RS, Garrity FL, Erickson AD, Corrao WM, Kaemmerlen JT. Sampling lower respiratory tract secretions in primary lung abscess: a comparison of the accuracy of four methods. Chest 1981; 79:559-65.  </p>      <p> 32. Bartlett JG. The technique of transtracheal aspiration.  J Crit Iln 1986; 1:43-9.  </p>      <p> 33. Bartlett JG. Diagnostic accuracy of transtracheal aspiration bacteriology. Am Rev Respir Dis 1977; 115:777-82.  </p>      <p> 34. Small PM, Fujiwara PI. Management of Tuberculosis in the United States.  N Engl J Med 2001; 345, n.º 3:189-200.   </p>      ]]></body>
<body><![CDATA[<p> 35. Landay MJ, Christensen EF, Bynum LJ, Goodman C. Anaerobic pleural and pulmonary infections.  AJA Am Roentgenol 1980; 134:233-40.  </p>      <p> 36. Bandt PD, Blank N, Castellino RA. Needle diagnosis of pneumonitis. Value in high-risk patients. JAMA 1972; 220:1578-80.  </p>      <p> 37. Wimberley NW, Bass JB, Boyd BW, <i>et al</i>. Use of a bronchoscopic protected catheter brush for the diagnosis of pulmonary infections.  Chest 1982; 81:556-62.  </p>      <p> 38. Gudiol F, Manresa F, Pallares R, <i>et al</i>.  Clindamicyn vs penicillin for anaerobic lung infections: high rate of penicillin failures associated with penicillin-resistant Bacteroides melaninogenicus. Arch Intern Med 1990; 150:2525-9.  </p>      <p> 39. Bartlett JG, Gorbach SL. Penicillin or clindamycin for primary lung abscess? Ann Intern Med 1983; 98:546-8.  </p>      <p> 40. Teng LJ, Hsueh PR, Tsai JC, Liaw SJ, Ho SW, Luh KT. High incidence of cefoxitin and clindamycin resistance among anaerobes in Taiwan. Antimicrob Agents Chemother 2002; 46:2908-13.  </p>      <p> 41. Appelbaum PC, Spangler SK, Jacobs MR. â-Lactamase production and susceptibilities to amoxicillin, amoxicillinclavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem and metronidazole of 320 non- Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 US centers. Antimicrob Agents Chemother 1990; 34:1546-50.  </p>      <p> 42. Smith DT. Medical treatment of acute and chronic pulmonary abscesses. J Thorac Surg 1942; 17:72-5.  </p>      <p> 43. Allen CI, Blackman JF. Treatment of lung abscess with report of 100 consecutive cases. J Thorac Surg 1936; 6:156-62.  </p>      <p> 44. Harber P, Terry PB. Fatal Lung Abscesses: Review of 11 years experience. South Med J 1981; 74:281-3.  </p>      ]]></body>
<body><![CDATA[<p> 45. Hagan JL, Hardy JD.  Lung abscess revisited: a survey of 184 cases. Ann Surg 1983; 197:755-62.  </p>      <p> 46. Pohlson EC, Mc Namara JJ, Char C, <i>et al</i>. Lung abscess: a changing pattern of the disease. Am J Surg 1985; 150:97-101.  </p>      <p> 47. Bartlett JG. Lung abscess. In Baum GL, Wolinsky E (Eds.). Textbook of Pulmonary Diseases. 5 th  ed. Boston, MA: Little Brown and Company, 1994; 607-20.   </p>        <p>&nbsp;</p>       <p>&nbsp;</p>        <p> <a name="1"></a><a href="#top1">1</a> Interna do Internato Complementar de    Medicina Interna, no Hospital de Santa Maria, Lisboa. </p>     <p> <a name="2"></a><a href="#top2">2</a> Assistente Hospitalar Graduado do Hospital    de Santa Maria, Cardiologista, Professor Auxiliar da Faculdade de Medicina de    Lisboa. </p>     <p> <a name="3"></a><a href="#top3">3</a> Professor Catedrático da Faculdade de    Medicina de Lisboa, Director do Serviço de Medicina 1 do Hospital de Santa Maria,    Lisboa. </p>     <p>Servi&ccedil;o de Medicina 1&#8211; sector C, Hospital de Santa Maria, Lisboa</p>     <p> Director: Professor Dr. Luciano Ravara </p>     ]]></body>
<body><![CDATA[<p>Avenida Professor Egas Moniz, 1649-035 Lisboa </p>     <p>e-mail: <a href="mailto:anapmgoncalves@gmail.com">anapmgoncalves@gmail.com</a></p>     <p>&nbsp;</p>     <p>Recebido para publicação/received for publication: 06.05.17</p>     <p>Aceite para publicação/accepted for publication: 07.09.12</p>       ]]></body><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Tan]]></surname>
<given-names><![CDATA[QT]]></given-names>
</name>
<name>
<surname><![CDATA[Seilheimer]]></surname>
<given-names><![CDATA[DK.]]></given-names>
</name>
<name>
<surname><![CDATA[Kaplan]]></surname>
<given-names><![CDATA[SL.]]></given-names>
</name>
</person-group>
<article-title xml:lang="en"><![CDATA[Pediatric lung abscess: clinical management and outcome.]]></article-title>
<source><![CDATA[Pediatric Infect Dis J]]></source>
<year>1995</year>
<volume>14</volume>
<page-range>51-5</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
