Sérgia Soares 1
Ana Carriço 2
Joana Sobrinho Simões 4
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Resumo
Apesar da ampla cobertura vacinal, a infecção por Bordetella pertussis está longe de estar controlada. Os recém -nascidos e lactentes ainda sem imunização completa e filhos de mães com baixos títulos de anticorpos para a Bordetella pertussis são altamente susceptíveis à infecção e têm maior risco de doença grave e morte. A infecção por Bordetella pertussis associada a hipertensão pulmonar no recém -nascido é frequentemente fatal.
Os autores descrevem um caso clínico de doença grave num recém -nascido com insuficiência respiratória aguda e hipertensão pulmonar grave, tratado com sucesso com sildenafil e óxido nítrico inalado.
Palavras -chave: Recém -nascido, oxido nítrico, pertussis, hipertensão pulmonar, sildenafil.
Pertussis with severe pulmonary hypertension in a newborn with good outcome – case report
Abstract
In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal.
]]> The authors report a clinical case of severe pertussis-induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.Key-words: Neonate, nitric oxide, pertussis, pulmonary hypertension, sildenafil.
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Full text only available in PDF format.
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]]> 1 Division of Neonatology, Department of Pediatrics
2 Division of Pediatric Cardiology, Department of Pediatrics
3 Unit of Pediatric Pulmonology, Department of Pediatrics
4 Molecular Biopathology Laboratory, Department of Clinical Pathology
* Faculty of Medicine of Porto University, Porto, Portugal
Correspondence:
Gustavo Rocha
Serviço de Neonatologia / Departamento de Pediatria Hospital de São João – Piso 2 Alameda Prof. Hernâni Monteiro
4202 – 451 Porto Portugal
Tel: +351 225095816
]]> Fax: +351225512273E -mail: gusrocha@oninet.pt
Recebido para publicação/received for publication: 08.02.22
Aceite para publicação/accepted for publication: 08.05.27
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