<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0873-2159</journal-id>
<journal-title><![CDATA[Revista Portuguesa de Pneumologia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Port Pneumol]]></abbrev-journal-title>
<issn>0873-2159</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Pneumologia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0873-21592008000600013</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Padrão de crazy-paving na leptospirose pulmonar: Correlação entre a tomografia computadorizada de alta resolução e os achados anatomopatológicos]]></article-title>
<article-title xml:lang="en"><![CDATA[Leptospirosis of the lung presenting with crazy-paving pattern: Correlation between the high-resolution CT and pathological findings]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Marchiori]]></surname>
<given-names><![CDATA[Edson]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gasparetto]]></surname>
<given-names><![CDATA[Taisa Davaus]]></given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Escuissato]]></surname>
<given-names><![CDATA[Dante L]]></given-names>
</name>
<xref ref-type="aff" rid="A03"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zanetti]]></surname>
<given-names><![CDATA[Gláucia]]></given-names>
</name>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,UFF - Universidade Federal Fluminense Departamento de Radiologia ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A02">
<institution><![CDATA[,UFRJ - Universidade Federal do Rio de Janeiro Departamento de Radiologia ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A03">
<institution><![CDATA[,Universidade Federal do Paraná Departamento de Radiologia ]]></institution>
<addr-line><![CDATA[Curitiba ]]></addr-line>
<country>Brasil</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2008</year>
</pub-date>
<volume>14</volume>
<numero>6</numero>
<fpage>887</fpage>
<lpage>891</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S0873-21592008000600013&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S0873-21592008000600013&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S0873-21592008000600013&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Os autores apresentam os aspectos na tomografia computadorizada de alta resolução de um doente com hemorragia pulmonar difusa por leptospirose. O achado predominante consistiu de opacidades em vidro despolido difusas, com espessamento de septos interlobulares sobrepostos, resultando no padrão de crazy-paving. O doente morreu, e na necrópsia foi observada extensa hemorragia alveolar, com sangue infiltrando os septos interlobulares. É realçada a correlação entre os achados anatomopatológicos e na tomografia computadorizada de alta resolução.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[The authors present the high-resolution CT findings of a patient with diffuse pulmonary hemorrhage due to leptospirosis. The main finding consisted of extensive ground-glass opacities super imposed on mild interlobular septal thickening, resulting in the appearance termed “crazy-paving”. The patient died and the necropsy showed extensive haemorrhage filling the airspace and blood infiltrating the interlobular septa. The correlation between the high-resolution CT and pathological findings is emphasised.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Leptospirose]]></kwd>
<kwd lng="pt"><![CDATA[hemorragia pulmonar]]></kwd>
<kwd lng="pt"><![CDATA[padrão de crazy-paving]]></kwd>
<kwd lng="pt"><![CDATA[tomografia computadorizada de alta resolução]]></kwd>
<kwd lng="en"><![CDATA[Leptospirosis]]></kwd>
<kwd lng="en"><![CDATA[pulmonary haemorrhage]]></kwd>
<kwd lng="en"><![CDATA[crazy-paving pattern]]></kwd>
<kwd lng="en"><![CDATA[high resolution CT]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <p><b>Padrão de <i>crazy-paving </i>na leptospirose pulmonar: Correlação entre    a tomografia computadorizada de alta resolução e os achados anatomopatológicos</b></p>      <p>&nbsp;</p>          <p><b>Edson Marchiori<sup><a href="#1">1</a><a name="top1"></a></sup></b></p>      <p><b>Taisa Davaus Gasparetto<sup><a href="#2">2</a><a name="top2"></a></sup></b></p>      <p><b>Dante L Escuissato<sup><a href="#3">3</a><a name="top3"></a></sup></b></p>      <p><b>Gláucia Zanetti<sup><a href="#4">4</a><a name="top4"></a></sup></b></p>          <p>&nbsp;</p>     <p>&nbsp;</p>     <p><b>Resumo</b></p>      <p>Os autores apresentam os aspectos na tomografia computadorizada de alta resolução    de um doente com hemorragia pulmonar difusa por leptospirose. O achado predominante    consistiu de opacidades em vidro despolido difusas, com espessamento de septos    interlobulares sobrepostos, resultando no padrão de <i>crazy-paving. </i>O doente    morreu, e na necrópsia foi observada extensa hemorragia alveolar, com sangue    infiltrando os septos interlobulares. É realçada a correlação entre os achados    anatomopatológicos e na tomografia computadorizada de alta resolução.</p>     ]]></body>
<body><![CDATA[<p><b>Palavras-chave: </b>Leptospirose, hemorragia pulmonar, padrão de <i>crazy-paving,    </i>tomografia computadorizada de alta resolução.</p>          <p>&nbsp;</p>     <p>&nbsp;</p>     <p><b>Leptospirosis of the lung presenting with crazy-paving pattern: Correlation    between the high-resolution CT and pathological findings</b></p>     <p><b>Abstract</b></p>      <p>The authors present the high-resolution CT findings of a patient with diffuse pulmonary hemorrhage due to leptospirosis. The main finding consisted of extensive ground-glass opacities super imposed on mild interlobular septal thickening, resulting in the appearance termed “crazy-paving”. The patient died and the necropsy showed extensive haemorrhage filling the airspace and blood infiltrating the interlobular septa. The correlation between the high-resolution CT and pathological findings is emphasised.</p>              <p><b>Key-words: </b>Leptospirosis, pulmonary haemorrhage, crazy-paving pattern,    high resolution CT.</p>     <p>&nbsp;</p>     <p>&nbsp;</p>      <p>Texto completo dispon&iacute;vel apenas em PDF.</p>     ]]></body>
<body><![CDATA[<p>Full text only available in PDF format.</p>     <p>&nbsp;</p>     <p>&nbsp;</p>     <p><b>Bibliography</b></p>      <!-- ref --><p>1. Luks AM, Lakshminarayanan S, Hirsch mann JV. Leptospirosis presenting as    diffuse alveolar hemorrhage: case report and literature review. Chest 2003;    123(2):639-43.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000027&pid=S0873-2159200800060001300001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><p>2. Arokianathan D, Trower K, Pooboni S, Sosnowski A, Moss P, Thaker H. Leptospirosis: a case report of a patient with pulmonary haemorrhage successfully managed with extra corporeal membrane oxygenation. J Infect 2005;50(2):158-62.</p>      <p>3. Carvalho JE, Marchiori ES, Guedes e Silva JB, Souza Netto BA, Tavares W, Paula AV. Pulmonary compromisse in leptospirosis. Rev Soc Bras Med Trop 1992; 25(4): 21-30.</p>      <p>4. Marchiori E, Muller NL. Leptospirosis of the lung: high-resolution computed    tomography findings in five patients. J Thorac Imaging 2002;17(2):151-153.</p>     <p>5. Im JG, Yeon KM, Han MC, Kim CW, Webb WR, Lee JS, <i>et al. </i>Leptospirosis    of the lung: radiographic findings in 58 patients. AJR 1989; 152(5):955-9.</p>      <p>6. Murch CR, Carr DH. Computed tomography appearances of pulmonary alveolar proteinosis. Clin Radiol 1989; 40(3):240-3.</p>      ]]></body>
<body><![CDATA[<p>7. Johkoh T, Itoh H, Müller NL, Ichikado K, Nakamura H, Ikezoe J, <i>et al. </i>Crazy paving appearance at thin-section CT: spectrum of disease and pathologic findings. Radiology 1999; 211(1):155-60.</p>      <p>8. Murayama S, Murakami J, Yabuuchi H, Soeda H, Masuda K. Crazy paving appearance on high resolution CT in various diseases. J Comput Assist Tomogr 1999; 23(5): 749-52.</p>      <p>9. Nicodemo AC, Duarte MI, Alves V, Takakura CFH, Santos RTM, Nicodemo EL. Lung lesions in human leptospirosis: microscopic, immunohistochemical, and ultrastructural features related to thrombocytopenia. Am J Trop Med Hyg 1997; 56(2):181-7.</p>      <p>10. Arean VM. The pathologic anatomy and pathogenesis of fatal human leptospirosis    (Weil’s disease). Am J Pathol 1962;40: 393-423.</p>      <p>&nbsp;</p>     <p>&nbsp;</p>     <p><sup><a name="1"></a><a href="#top1">1</a></sup> Professor Titular e Chefe    do Departamento de Radiologia da Universidade Federal Fluminense (UFF). Coordenador    Adjunto do Curso de Pós-Graduação em Radiologia da Universidade Federal do Rio    de Janeiro (UFRJ) / <i>Full Professor, Head, Department of Radiology of the    University Fluminense (UFF). Associate Coordinator, Post-Graduate Course in    Radiology, University of Rio de Janeiro (UFRJ).</i></p>     <p><sup><a name="2"></a><a href="#top2">2</a></sup> Médica Pós-Graduanda do Departamento    de Radiologia da UFF / <i>Post-Graduate Doctor, Department of Radiology, UFF.</i></p>     <p><sup><a name="3"></a><a href="#top3">3</a></sup> Professor Adjunto de Radiologia    da Universidade Federal do Paraná, Curitiba, Brasil / <i>Associate Professor    of Radiology, University of Paraná, Brazil.</i></p>     <p><sup><a name="4"></a><a href="#top4">4</a></sup> Doutoranda em Radiologia da    UFRJ / <i>PhD in Radiology, UFRJ.</i></p>     ]]></body>
<body><![CDATA[ ]]></body><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Luks]]></surname>
<given-names><![CDATA[AM]]></given-names>
</name>
<name>
<surname><![CDATA[Lakshminarayanan]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Hirsch mann]]></surname>
<given-names><![CDATA[JV.]]></given-names>
</name>
</person-group>
<article-title xml:lang="en"><![CDATA[Leptospirosis presenting as diffuse alveolar hemorrhage: case report and literature review]]></article-title>
<source><![CDATA[Chest]]></source>
<year>2003</year>
<volume>123</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>639-43</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
