Marco Machado
Felipe Sampaio-Jorge
André Teixeira- Ferreira
Franz W. Knifis
Laboratório de Fisiologia e Biocinética Universidade Iguaçu (UNIG, Itaperuna)
]]> Resumo
Exercícios são indutores de aumentos na concentração sérica de CK, indicador de microlesões, sendo especulado que o uso da suplementação de creatina potencializaria este efeito. O objetivo deste estudo foi verificar se a suplementação de creatina modifica a concentração de CK em sedentários submetidos a exercícios. Vinte e sete homens sedentários, entre 18 e 25 anos participaram de um estudo duplo-cego placebo controlado. No primeiro dia todos foram submetidos a uma avaliação cineantropométrica e nutricional e posteriormente divididos aleatoriamente em 2 grupos: C (n = 15) e P (n = 12). Depois da suplementação todos foram submetidos a um programa de 5 exercícios (3x10 repetições) a 85% de 1RM. Os sujeitos tiveram a concentração de CK medida antes da suplementação, imediatamente antes, 4h e 24h após os exercícios. Houve aumento na MCT dos sujeitos suplementados com creatina (0,7 ± 0,3 kg). Não houve aumento da variação da concentração de CK medida após a suplementação e após o exercício, contudo a concentração de CK aumentou 24h após em ambos os grupos (253 ± 27% no grupo C e 262 ± 31% no grupo P). A diferença da concentração de CK pós-exercício (24h) foi maior em ambos os grupos analisados neste estudo sem, no entanto mostrar efeito da suplementação.
Palavras chave: microlesão muscular; lesão induzida por exercício; suplementação de creatina; CK
Serum CK concentration is modulated by exercise but not creatine supplementation
Abstract
Exercises are inductive of increases in serun CK concentration, microinjuries marker, being speculated that the use of creatine supplementation would increases this effect. The aim of this study was to verify if creatine supplementation modifies the concentration of CK in sedentary submitted the exercises. Twenty seven sedentary men, between 18 and 25 years had participated of controlled a double-blind study placebo. In the first day all had been submitted to a evaluation and later divided in 2 groups: C (n = 15) and P (n = 12). After the supplementation all had been submitted to a program of 5 exercises (3x10 repetitions) 85% of 1RM. The subjects had the concentration of CK measured before the suplementação, immediately before, 4h and 24h after the exercises. It had increase in the MCT of the subjects supplemented with creatine (0,7 ± 0,3 kg). the variation of the concentration of CK did not have increase of measured after the supplementation and after the exercise, however the CK concentration after increased 24h in both the groups (253 ± 27% in 262 group C and ± 31% in group P). The difference of the CK concentration after-exercise (24h) was bigger in both the groups analyzed in this study without, however to show effect of the supplementation.
Key words: muscle damage; exercise induced injury; creatine supplementation; CK
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Data de submissão: Dezembro 2007
Data de Aceite: Abril 2007
Correspondência:
Marco Machado
Laboratório de Fisiologia e Biocinética (UNIG – Campus V)
BR 356 - Km 02 Itaperuna, RJ, 28.300-000
Brasil
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