<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1646-2890</journal-id>
<journal-title><![CDATA[Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Port Estomatol Med Dent Cir Maxilofac]]></abbrev-journal-title>
<issn>1646-2890</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Estomatologia e Medicina Dentária]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1646-28902020000200057</article-id>
<article-id pub-id-type="doi">10.24873/j.rpemd.2020.09.703</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[The role of hyaluron acid in non-surgical treatment of Chronic Periodontitis - Systematic review]]></article-title>
<article-title xml:lang="pt"><![CDATA[O papel do ácido hialurónico no tratamento não cirúrgico da periodontite crónica - Revisão sistemática]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodrigues]]></surname>
<given-names><![CDATA[Vanessa Rocha]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rocha]]></surname>
<given-names><![CDATA[Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Otão]]></surname>
<given-names><![CDATA[Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Luis]]></surname>
<given-names><![CDATA[Henrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Noronha]]></surname>
<given-names><![CDATA[Susana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mascarenhas]]></surname>
<given-names><![CDATA[Paulo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Faculdade de Medicina Dentária de Lisboa  ]]></institution>
<addr-line><![CDATA[Lisboa ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidade de Lisboa Faculdade de Medicina Dentária Departamento de Higiene Oral]]></institution>
<addr-line><![CDATA[Lisboa ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,FMDUL Departamento de Periodontologia ]]></institution>
<addr-line><![CDATA[Lisboa ]]></addr-line>
<country>Portugal</country>
</aff>
<pub-date pub-type="pub">
<day>30</day>
<month>06</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>06</month>
<year>2020</year>
</pub-date>
<volume>61</volume>
<numero>2</numero>
<fpage>57</fpage>
<lpage>63</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S1646-28902020000200057&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S1646-28902020000200057&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S1646-28902020000200057&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Objectives:  The purpose of this review is to perform a systematic evaluation of the clinical effects of the local subgingival use of 0.8% or 0.2% hyaluronic acid (HA) as an adjunct to scaling and root planning in patients with chronic periodontitis.  Methods:  An electronic search was performed on PubMed, Lilacs, and Cochrane, without any time or language restrictions, on May 9, 2018, using the following keywords: &#8220;hyaluronic acid&#8221;; &#8220;periodontitis&#8221;; &#8220;treatment of periodontitis&#8221;; and &#8220;scaling.&#8221; The following parameters were evaluated: clinical attachment level (CAL) gain, probing depth (PD), bleeding on probing (BOP), plaque index (PI), and gingival index (IG). This review was registered with the identification number CRD42019131541 in the PROSPERO International Prospective Register of Systematic Reviews hosted by the National Institute for Health Research, University of York, Centre for Reviews and Dissemination.  Results:  When applied to periodontitis, the combined treatment HA + SRP provides more satisfactory results than the conventional treatment of SRP alone in most of the outcome variables presented.  Conclusion:  It can be concluded that hyaluronic acid is a chemical adjuvant to consider in periodontal therapy.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo  Objetivos:  O objetivo desta revisão foi realizar uma análise sistemática que avalie os efeitos clínicos e microbiológicos do uso local subgengival de HA 0,8% ou 0,2% como adjuvante ao alisamento radicular em pacientes com periodontite crónica.  Métodos:  Foi realizada uma pesquisa eletrónica nas seguintes bases de dados: PubMed, Lilacs e Chocrane sem restrições de tempo ou idioma, até 9 de Maio de 2018. Foram utilizadas as seguintes palavra-chave (&#8220;ácido hialurónico&#8221;; &#8220;periodontite&#8221;; &#8220;tratamento da periodontite&#8221;; &#8220;alisamento radicular&#8221;). Os seguintes parâmetros clínicos foram avaliados, nível de inserção clínica, profundidade de sondagem, hemorragia à sondagem, índice de placa e índice gengival. A revisão foi registrada com o número de identificação CRD42019131541, no PROSPERO International Prospective Register of Sistemmatic Reviews, hospedado pelo Instituto Nacional de Pesquisa em Saúde, Universidade de York, Centro de Revisões e Disseminação.  Resultados:  A combinação da aplicação ácido hialurónico com o alisamento radicular, apresenta resultados clínicos mais satisfatórios, quando comparados com o alisamento radicular isolado.  Conclusões:  Pode-se concluir que o ácido hialurónico é um adjuvante químico a considerar na terapia periodontal.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Hyaluronic acid]]></kwd>
<kwd lng="en"><![CDATA[Periodontitis]]></kwd>
<kwd lng="en"><![CDATA[Scaling]]></kwd>
<kwd lng="en"><![CDATA[Treatment of periodontitis]]></kwd>
<kwd lng="pt"><![CDATA[Ácido hialurónico]]></kwd>
<kwd lng="pt"><![CDATA[Periodontite]]></kwd>
<kwd lng="pt"><![CDATA[Alisamento]]></kwd>
<kwd lng="pt"><![CDATA[Tratamento da periodontite]]></kwd>
</kwd-group>
</article-meta>
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