<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1646-2890</journal-id>
<journal-title><![CDATA[Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Port Estomatol Med Dent Cir Maxilofac]]></abbrev-journal-title>
<issn>1646-2890</issn>
<publisher>
<publisher-name><![CDATA[Sociedade Portuguesa de Estomatologia e Medicina Dentária]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1646-28902024000400205</article-id>
<article-id pub-id-type="doi">10.24873/j.rpemd.2024.12.1410</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Tuberculosis of the tongue in a patient under treatment with adalimumab]]></article-title>
<article-title xml:lang="pt"><![CDATA[Tuberculose na língua em doente em tratamento com adalimumabe]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Milani]]></surname>
<given-names><![CDATA[Cintia Mussi]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arana]]></surname>
<given-names><![CDATA[Rafaela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Melzer]]></surname>
<given-names><![CDATA[Rafaela Sávio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lima]]></surname>
<given-names><![CDATA[Antônio Adilson Soares]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Machado]]></surname>
<given-names><![CDATA[Maria Angela Naval]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Roskamp]]></surname>
<given-names><![CDATA[Liliane]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidade Tuiuti do Paraná Faculty of Dentistry ]]></institution>
<addr-line><![CDATA[Curitiba Paraná]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Private Practice  ]]></institution>
<addr-line><![CDATA[Curitiba Paraná]]></addr-line>
<country>Brazil</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2024</year>
</pub-date>
<volume>65</volume>
<numero>4</numero>
<fpage>205</fpage>
<lpage>208</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_arttext&amp;pid=S1646-28902024000400205&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_abstract&amp;pid=S1646-28902024000400205&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.pt/scielo.php?script=sci_pdf&amp;pid=S1646-28902024000400205&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Tuberculosis is a chronic infectious disease that may affect any part of the body, including the oral cavity. Among the predisposing factors to the disease, adalimumab, a monoclonal antibody used as an effective therapy in patients with rheumatic disorders, including psoriatic arthritis, increases the risk of active tuberculosis development. Oral tuberculosis is relatively rare and usually manifests as a persistent oral ulcer. Dentists are at the frontline to diagnose oral lesions and should always consider tuberculosis in the differential diagnosis of a persistent oral ulcer, especially in patients under adalimumab. We present a case of tuberculosis of the tongue in a 50-year-old male under treatment with adalimumab for five years to treat psoriatic arthritis.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo A tuberculose é uma doença infeciosa crónica que pode afetar qualquer parte do corpo, incluindo a cavidade oral. Entre os fatores que predispõem para a doença, o adalimumabe, um anticorpo monoclonal utilizado como terapêutica eficiente em doentes com perturbações reumáticas, incluindo a artrite psoriática, aumenta o risco de desenvolvimento de tuberculose ativa. A tuberculose oral é relativamente rara e geralmente manifesta-se como uma úlcera persistente. Os médicos dentistas estão na linha da frente do diagnóstico das lesões orais e devem sempre considerar a tuberculose no diagnóstico diferencial de úlceras persistentes, especialmente em doentes em tratamento com adalimumabe. Apresentamos um caso de tuberculose na língua num homem de 50 anos que estava a ser tratado com adalimumabe há 5 anos.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Adalimumab]]></kwd>
<kwd lng="en"><![CDATA[Oral tuberculosis]]></kwd>
<kwd lng="en"><![CDATA[Oral ulcer]]></kwd>
<kwd lng="pt"><![CDATA[Adalimumabe]]></kwd>
<kwd lng="pt"><![CDATA[Tuberculose oral]]></kwd>
<kwd lng="pt"><![CDATA[Úlcera oral]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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